Evidence map›Paper›PMID 38811348›Full record

ArticlePhysiological reports2024

Effects of astaxanthin on gut microbiota of polo ponies during deconditioning and reconditioning periods.

Mia Y Kawaida, Kendra R Maas, Timothy E Moore, Amanda S Reiter, Nicole M Tillquist, Sarah A Reed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mia Y KawaidaDepartment of Animal Science, University of Connecticut, Storrs, Connecticut, USA.
Kendra R MaasMicrobial Analysis, Resources, and Services, University of Connecticut, Storrs, Connecticut, USA.
Timothy E MooreStatistical Consulting Services, Center for Open Research Resources and Equipment, University of Connecticut, Storrs, Connecticut, USA.
Amanda S ReiterDepartment of Animal Science, University of Connecticut, Storrs, Connecticut, USA.
Nicole M TillquistDepartment of Animal Science, University of Connecticut, Storrs, Connecticut, USA.
Sarah A ReedDepartment of Animal Science, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0002-9961-6280

Funding

University of Connecticut Research Excellence Program
6 · The paper itself

Abstract

To determine the effects of astaxanthin (ASTX) supplementation on the equine gut microbiota during a deconditioning-reconditioning cycle, 12 polo ponies were assigned to a control (CON; n = 6) or supplemented (ASTX; 75 mg ASTX daily orally; n = 6) group. All horses underwent a 16-week deconditioning period, with no forced exercise, followed by a 16-week reconditioning program where physical activity gradually increased. Fecal samples were obtained at the beginning of the study (Baseline), after deconditioning (PostDecon), after reconditioning (PostRecon), and 16 weeks after the cessation of ASTX supplementation (Washout). Following DNA extraction from fecal samples, v4 of 16S was amplified and sequenced to determine operational taxonomic unit tables and α-diversity and β-diversity indices. The total number of observed species was greater at Baseline than PostDecon, PostRecon, and Washout (p ≤ 0.02). A main effect of ASTX (p = 0.01) and timepoint (p = 0.01) was observed on β-diversity, yet the variability of timepoint was greater (13%) than ASTX (6%), indicating a greater effect of timepoint than ASTX. Deconditioning and reconditioning periods affected the abundance of the Bacteroidetes and Fibrobacteres phyla. Physical activity and ASTX supplementation affect the equine gut microbiome, yet conditioning status may have a greater impact.

Indexed as

Dietary SupplementsGastrointestinal MicrobiomePhysical Conditioning, AnimalXanthophyllsAnimalsFecesFemaleHorsesMaleastaxanthineXanthophyllsastaxanthindeconditioninggut microbiotahorsereconditioning

Identifiers

PMID38811348
PMCPMC11136553

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.