Evidence map›Paper›PMID 38811167›Full record

ArticleOccupational and environmental medicine2024

Occupational particle exposure and chronic kidney disease: a cohort study in Swedish construction workers.

Karl Kilbo Edlund, Eva M Andersson, Martin Andersson, Lars Barregard, Anders Christensson, Sandra Johannesson, Florencia Harari, Nicola Murgia, Kjell Torén, Leo Stockfelt

Abstract read
In one paragraph

Article in Occupational and environmental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Occupational particle exposure and diabetes: a cohort study in Swedish construction workers.International archives of occupational and environmental health · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karl Kilbo EdlundSchool of Public Health and Community Medicine, University of Gothenburg, Goteborg, Sweden karl.kilbo.edlund@gu.se.ORCID 0000-0001-7586-4119
Eva M AnderssonSchool of Public Health and Community Medicine, University of Gothenburg, Goteborg, Sweden.
Martin AnderssonDepartment of Public Health and Clinical Medicine, Umeå University, Umea, Sweden.
Lars BarregardSchool of Public Health and Community Medicine, University of Gothenburg, Goteborg, Sweden.
Anders ChristenssonDepartment of Nephrology, Lund University, Lund, Sweden.
Sandra JohannessonSchool of Public Health and Community Medicine, University of Gothenburg, Goteborg, Sweden.ORCID 0000-0002-9557-8918
Florencia HarariSchool of Public Health and Community Medicine, University of Gothenburg, Goteborg, Sweden.ORCID 0000-0002-0362-579X
Nicola MurgiaDepartment of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy.
Kjell TorénSchool of Public Health and Community Medicine, University of Gothenburg, Goteborg, Sweden.ORCID 0000-0001-8509-7603
Leo StockfeltSchool of Public Health and Community Medicine, University of Gothenburg, Goteborg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIncreasing epidemiological and experimental evidence suggests that particle exposure is an environmental risk factor for chronic kidney disease (CKD). However, only a few case-control studies have investigated this association in an occupational setting. Hence, our objective was to investigate associations between particle exposure and CKD in a large cohort of Swedish construction workers.

methodsWe performed a retrospective cohort study in the Swedish Construction Workers' Cohort, recruited 1971-1993 (n=286 089). A job-exposure matrix was used to identify workers exposed to nine different particulate exposures, which were combined into three main categories (inorganic dust and fumes, wood dust and fibres). Incident CKD and start of renal replacement therapy (RRT) were obtained from validated national registries until 2021 and analysed using adjusted Cox proportional hazards models.

resultsExposure to inorganic dust and fumes was associated with an increased risk of CKD and RRT during working age (adjusted HR for CKD at age <65 years 1.15, 95% CI 1.05 to 1.26). The elevated risk did not persist after retirement age. Exposure to cement dust, concrete dust and diesel exhaust was associated with CKD. Elevated HRs were also found for quartz dust and welding fumes.

conclusionsWorkers exposed to inorganic particles seem to be at elevated risk of CKD and RRT. Our results are in line with previous evidence of renal effects of ambient air pollution and warrant further efforts to reduce occupational and ambient particle exposure.

Indexed as

Construction IndustryDustOccupational DiseasesOccupational ExposureRenal Insufficiency, ChronicAdultAgedAir Pollutants, OccupationalCohort StudiesConstruction MaterialsFemaleHumansMaleMiddle AgedParticulate MatterProportional Hazards ModelsAir Pollutants, OccupationalDustParticulate MatterVehicle EmissionsDustEpidemiologyKidney Diseases

Identifiers

PMID38811167
PMCPMC11187372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.