Evidence map›Paper›PMID 38810092›Full record

ArticleJournal of applied clinical medical physics2024

Dosimetric characterization for GRID collimator-based spatially fractionated radiation therapy: Dosimetric parameter acquisition and machine interchangeability investigation.

Zhengzheng Xu, Salim Balik, Kaley Woods, Zhilei Shen, Chihyao Cheng, Jing Cui, Haihong Gallogly, Eric Chang, Lauren Lukas, Andrew Lim and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zhengzheng XuKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Salim BalikKeck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-0756-8953
Kaley WoodsKeck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-6189-0313
Zhilei ShenKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Chihyao ChengDepartment of Radiation Oncology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.
Jing CuiKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Haihong GalloglyKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Eric ChangKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Lauren LukasKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Andrew LimKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Yutaka NatsuakiKeck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0009-0003-8754-3250
Jason YeKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Lijun MaKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Hualin ZhangKeck School of Medicine, University of Southern California, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to characterize the dosimetric properties of a commercial brass GRID collimator for high energy photon beams including 15 and 10 MV. Then, the difference in dosimetric parameters of GRID beams among different energies and linacs was evaluated.

methodA water tank scanning system was used to acquire the dosimetric parameters, including the percentage depth dose (PDD), beam profiles, peak to valley dose ratios (PVDRs), and output factors (OFs). The profiles at various depths were measured at 100 cm source to surface distance (SSD), and field sizes of 10 × 10 cm

resultsCompared with the open beam data, there were noticeable changes in PDDs of GRID fields across all the energies. The GRID fields demonstrated a maximal of 3 mm shift in dmax (Truebeam STX, 15MV, 10 × 10 cm

conclusionThe dosimetric characteristics of high-energy GRID fields, especially PVDR, significantly differ from those of low-energy GRID fields. Two Truebeam machines are interchangeable for GRID therapy, while a pronounced difference was observed between Truebeam and Trilogy. A series of empirical equations and reference look-up tables for GRID therapy can be generated to facilitate clinical applications.

Indexed as

NeoplasmsParticle AcceleratorsPhotonsRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedDose Fractionation, RadiationHumansMonte Carlo MethodPhantoms, ImagingRadiotherapy, Intensity-ModulatedGRID collimatorGRID therapypeak valley dose ratiospatially fractionated radiation therapy

Identifiers

PMID38810092
PMCPMC11302805

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.