ArticleScience advances2024
Abstract read
In one paragraph
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Methionine Regulates Antitumour Function of CD8Immunology · 2026Article
- Metabolic profiling of CAR T-cells in patients reveals a shift toward amino acid-supported OXPHOS and informs transporter engineering.Research square · 2026Article
- Article
- Plasmacytoid Dendritic Cells Exhibit High Transferrin Receptor Expression Without Iron Accumulation.European journal of immunology · 2026Article
- Glioblastoma cells utilize evolutionarily adapted cell metabolism to promote their malignant proliferation.Acta neuropathologica communications · 2026Article
- Metabolic and transcriptional plasticity supports CD8Immunity · 2026Article
- Metabolic modulation of immune cell function: mechanisms and therapeutic implications in cancer immunotherapy.Oncogenesis · 2026Review
- Endogenous CD28 Drives the Persistent Activity of CAR T Cells in Myeloma and Lymphoma Models.Blood cancer discovery · 2026Article
- A Stable Isotope Tracing Primer for the Mass Spectrometrist.Annual review of analytical chemistry (Palo Alto, Calif.) · 2026Review
- Article
- Aspartate availability drives differential engagement of the malate-aspartate shuttle.Molecular cell · 2026Article
- Distinct sensing of BCAAs by mTOR and c-Myc governs T cell proliferation, independent of catabolism.bioRxiv : the preprint server for biology · 2026Article
- Glucose availability tunes latent CD8+ T cell expansion potential through a mitogen-independent, mTOR-dependent regulatory switch.bioRxiv : the preprint server for biology · 2026Article
- Integrated metabolomics and machine learning identify predictive biomarkers via SHAP analysis for sintilimab-induced rash in lung cancer patients.Frontiers in pharmacology · 2026Article
- Integrating T cell signaling and metabolism to enhance T cell engager responses in solid tumors.Frontiers in immunology · 2026Review
- Redox-metabolic circuits as a central regulator of T cell-based immunotherapy.Frontiers in immunology · 2026Review
- AMPK agonism optimizes the in vivo activation and antileukemic efficacy of chimeric antigen receptor T cells.Journal for immunotherapy of cancer · 2025Article
- Dietary restriction reprograms CD8Nature metabolism · 2025Article
- Autophagy disruption primes CAR-T cell metabolism for sustained rejection of ovarian tumors.bioRxiv : the preprint server for biology · 2025Article
- Methionine regulates antitumor function of CD8bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
- Update of
Authors and funding
20 authors.
Eric H MaDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0001-8556-980X
Michael S DahabiehDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-2518-7129
Lisa M DeCampDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Irem KaymakDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0003-0772-512X
Susan M Kitchen-GoosenDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0001-9291-056X
Brandon M OswaldDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-4147-2915
Joseph LongoDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-9580-5105
Dominic G RoyCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada.ORCID 0000-0002-6044-0118
Mark J VerwayGoodman Cancer Institute, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Radia M JohnsonGilead Sciences Inc., Foster City, CA, USA.ORCID 0000-0002-9755-9307
Bozena SamborskaGoodman Cancer Institute, Faculty of Medicine, McGill University, Montréal, QC, Canada.ORCID 0000-0002-1871-4699
Lauren R DuimstraDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0001-5753-4108
Catherine A ScullionDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Mya SteadmanAgios Pharmaceuticals, Cambridge, MA, USA.
Matthew VosDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Thomas P RoddyAgios Pharmaceuticals, Cambridge, MA, USA.
Connie M KrawczykDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-2468-5986
Kelsey S WilliamsDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-4163-5075
Ryan D SheldonDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-1573-9719
Russell G JonesDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0003-2250-4675
Funding
Ketone Body Metabolism in CD8+ T Cell ResponsesR01AI165722 · NIAID · VAN ANDEL RESEARCH INSTITUTE · PI JONES, RUSSELL GRAHAM · 2022 to 2025
$3.3MChromatin architecture as a determinant of dendritic cell functionR21AI153997 · NIAID · VAN ANDEL RESEARCH INSTITUTE · PI KRAWCZYK, CONNIE · 2020 to 2021
$523kNIAID NIH HHS R01 AI165722NIAID NIH HHS R21 AI153997
Abstract
Infusion of
Indexed as
AcetatesCarbon IsotopesCD8-Positive T-LymphocytesGlutamineAnimalsCitric Acid CycleGlucoseListeria monocytogenesListeriosisMiceMice, Inbred C57BLAcetatesCarbon IsotopesGlucoseGlutamine
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LicenceCC BY-NC
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.