Evidence map›Paper›PMID 38809910›Full record

ArticlePLOS global public health2024

Structural and social factors affecting COVID-19 vaccine uptake among healthcare workers and older people in Uganda: A qualitative analysis.

Sande Slivesteri, Agnes Ssali, Ubaldo M Bahemuka, Denis Nsubuga, Moses Muwanga, Chris Nsereko, Edward Ssemwanga, Asaba Robert, Janet Seeley, Alison Elliott and 1 more

Abstract read
In one paragraph

Article in PLOS global public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sande SlivesteriMRC/UVRI & LSHTM Uganda Research Unit, Wakiso, Uganda.ORCID https://orcid.org/0000-0001-9463-5004
Agnes SsaliMRC/UVRI & LSHTM Uganda Research Unit, Wakiso, Uganda.ORCID https://orcid.org/0000-0003-4801-0411
Ubaldo M BahemukaMRC/UVRI & LSHTM Uganda Research Unit, Wakiso, Uganda.ORCID https://orcid.org/0000-0003-1092-4832
Denis NsubugaMRC/UVRI & LSHTM Uganda Research Unit, Wakiso, Uganda.
Moses MuwangaEntebbe Regional Referral Hospital, Wakiso, Uganda.
Chris NserekoEntebbe Regional Referral Hospital, Wakiso, Uganda.
Edward SsemwangaVilla Maria Hospital, Kalungu, Uganda.
Asaba RobertOur Lady of Consolata, Kisubi Hospital, Wakiso, Uganda.
Janet SeeleyMRC/UVRI & LSHTM Uganda Research Unit, Wakiso, Uganda.ORCID https://orcid.org/0000-0002-0583-5272
Alison ElliottMRC/UVRI & LSHTM Uganda Research Unit, Wakiso, Uganda.ORCID https://orcid.org/0000-0003-2818-9549
Eugene RuzagiraMRC/UVRI & LSHTM Uganda Research Unit, Wakiso, Uganda.

Funding

EPA EP-C-15-004Wellcome Trust
6 · The paper itself

Abstract

The COVID-19 vaccine rollout programme in Uganda was launched in March 2021 for priority groups: Healthcare Workers (HCWs), older persons (≥50 years), and persons with chronic conditions. Misinformation, distrust in healthcare systems, and cultural beliefs, pose significant challenges to vaccine uptake. We describe the social and structural factors affecting the uptake of COVID-19 vaccines among HCWs and older people in Uganda. Between September and October 2021, we conducted 33 in-depth interviews with 25 HCWs aged 21-63 years from three hospitals in central Uganda and eight older people from Wakiso district. Participant selection was purposive, based on sex, occupation, education, cadre of HCWs and vaccination status. We explored participants' knowledge, beliefs, personal experiences, barriers, and facilitators to vaccine uptake as well as suggestions for future COVID-19 vaccine rollout. Interviews were audio-recorded, transcribed and translated into English, coded, and analysed by theme. Twenty-two of the 25 (88%) HCWs and 3 of the 8 (38%) older people had received at least one dose of the COVID-19 vaccine at the time of interview. The structural facilitating factors to vaccine uptake included access to correct information, fear of a risky work environment, and mandatory vaccination requirements especially for frontline HCWs. Age, chronic health conditions, and the fear of death were facilitating factors for older people. Misconceptions about COVID-19 vaccines and fear of side effects were common social barriers for both groups. Long distances to vaccination centres, vaccine stock-outs, and long queues at the vaccination centres were specific barriers for older people. The prerequisite of signing a consent form was a specific structural barrier for HCWs. Future roll out of new vaccines should have a comprehensive information dissemination strategy about the vaccines. Improved access to vaccines through community outreach, reliable vaccine supplies and addressing vaccine misinformation, may enhance COVID-19 vaccine uptake.

Identifiers

PMID38809910
PMCPMC11135783

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.