Evidence map›Paper›PMID 38809846›Full record

ArticlePloS one2024

The one-minute sit-to-stand-test performance is associated with health-related quality of life in patients with pulmonary hypertension.

Christina Kronberger, Robin Willixhofer, Roya Anahita Mousavi, Mariusz Tadeusz Grzeda, Brigitte Litschauer, Christoph Krall, Roza Badr Eslam

Abstract read
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Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Christina KronbergerDepartment for Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.
Robin WillixhoferDepartment for Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3405-5715
Roya Anahita MousaviDepartment for Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-2730-9900
Mariusz Tadeusz GrzedaGalen Research, Manchester, United Kingdom.
Brigitte LitschauerDepartment for Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Christoph KrallCenter for Medical Data Science, Medical University of Vienna, Vienna, Austria.
Roza Badr EslamDepartment for Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0360-2360

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with pulmonary hypertension (PH) have an impaired functional capacity and poor health-related quality of life (HRQoL). The one-minute sit-to-stand test (1-min STST) can be used for the assessment of functional capacity.

aimsOur aim was to evaluate the 1-min STST performance and its association with patient-reported HRQoL in patients with PH.

methodsWe prospectively assessed functional capacity in 98 PH patients (mean age 66 ± 15 years, 55% female) using the 1-min STST. Patients had to stand up and sit down from a chair as many times as possible within one minute. Patients' HRQoL was evaluated with the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) questionnaire, which consists of the three subcategories symptoms, activities and quality of life (QoL).

resultsWe observed a significant correlation of the 1-min STST performance with all HRQoL subcategories assessed with the CAMPHOR questionnaire: A lower number of 1-min STST repetitions correlated with more symptoms (rs = -.398, p < .001), worse functioning (rs = -.551, p < .001) and a decreased QoL (rs = -.407, p < .001). Furthermore, in the multivariable linear regression analysis, adjusted for age, sex, body mass index (BMI) and mean pulmonary artery pressure (mPAP), lower 1-min STST performance was an independent predictor for worse symptoms (est. β = -0.112, p = .003), activities (est. β = -0.198, p < .001) and QoL (est. β = -0.130, p < .001) assessed with the CAMPHOR questionnaire.

conclusionOur results indicate that regardless of age, sex, BMI and mPAP the 1-min STST performance is associated with all CAMPHOR HRQoL subcategories in patients with PH. Therefore, the 1-min STST performance might be a new option to assess functional capacity correlated to HRQoL in patients with PH.

Indexed as

Hypertension, PulmonaryQuality of LifeAgedExercise TestFemaleHumansMaleMiddle AgedProspective StudiesSurveys and Questionnaires

Identifiers

PMID38809846
PMCPMC11135673

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.