ArticleAmerican journal of physiology. Endocrinology and metabolism2024
Adipocyte-specific inactivation of NAMPT, a key NAD
Abstract read
In one paragraph
Article in American journal of physiology. Endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging.Aging cell · 2026Article
- Keeping up with the nicotinamides: NADP(H), the forgotten circadian cofactor that keeps metabolic time.Life metabolism · 2025Review
- Nicotinamide phosphoribosyltransferase in NADCell death discovery · 2025Review
- A Comprehensive Multiomics Signature of Doxorubicin-Induced Cellular Senescence in the Postmenopausal Human Ovary.Aging cell · 2025Article
- Weight of time: exploring the link between obesity and aging.Aging clinical and experimental research · 2025Review
- DNA damage in proximal tubules triggers systemic metabolic dysfunction through epigenetically altered macrophages.Nature communications · 2025Article
- PRKDC regulates cGAMP to enhance immune response in lung cancer treatment.Frontiers in immunology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Nathan QiDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States.
Michael P FranczykCenter for Human Nutrition, Washington University School of Medicine, St. Louis, Missouri, United States.
Shintaro YamaguchiCenter for Human Nutrition, Washington University School of Medicine, St. Louis, Missouri, United States.
Daiki KojimaDivision of Endocrinology, Metabolism and Nephrology Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-2906-676X
Kaori HayashiDivision of Endocrinology, Metabolism and Nephrology Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Akiko SatohDepartment of Integrative Physiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Noboru OgisoLaboratory of Experimental Animals, National Center for Geriatrics and Gerontology, Obu, Japan.
Takeshi KandaDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, Izumo, Japan.
Yo SasakiDepartment of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States.
Brian N FinckCenter for Human Nutrition, Washington University School of Medicine, St. Louis, Missouri, United States.ORCID 0000-0001-5411-3674
Brian J DeBoschDepartment of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States.ORCID 0000-0002-9924-7921
Jun YoshinoCenter for Human Nutrition, Washington University School of Medicine, St. Louis, Missouri, United States.ORCID 0000-0001-9833-4356
Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0MWU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8MWashington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2MWU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Jennifer Lynn Powers Carson · 2013 to 2026
$27.1MRegional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3MREGULATION OF SYSTEMIC GLUCOSE AND LIPID HOMEOSTASIS BY ADIPOCYTE NAD BIOSYNTHESISR01DK104995 · NIDDK · WASHINGTON UNIVERSITY · PI KLEIN, SAMUEL · 2016 to 2024
$3.5MTreating secondary cardiomyopathies by mimicking the adaptive hepatic glucose fasting responseR01HL147968 · NHLBI · WASHINGTON UNIVERSITY · PI DEBOSCH, BRIAN JESSE · 2020 to 2024
$3.2MNOVEL ASPECTS OF HEPATIC MITOCHONDRIAL AMINO ACID METABOLISMR01DK117657 · NIDDK · WASHINGTON UNIVERSITY · PI FINCK, BRIAN N · 2018 to 2022
$1.9MLeveraging arginase biology against metabolic diseaseR01DK131009 · NIDDK · WASHINGTON UNIVERSITY · PI Brian Jesse DeBosch · 2023 to 2026
$1.7MLeveraging glucose transport and the adaptive fasting response to modulate hepatic metabolismR01DK126622 · NIDDK · WASHINGTON UNIVERSITY · PI DEBOSCH, BRIAN JESSE · 2021 to 2024
$1.7MLeveraging glucose transport and the adaptive fasting response to modulate hepatic metabolismR56DK115764 · NIDDK · WASHINGTON UNIVERSITY · PI DEBOSCH, BRIAN JESSE · 2018 to 2018
$381kAstellas Pharma (Astellas)HHS | NIH | National Cancer Institute (NCI) P30CA091842HHS | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR002345HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL147968HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P30DK020572HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P30DK020579HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P30DK056341HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK117657HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R0DK104995HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R0DK126622HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R0DK131009HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R56DK115764HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) U2CDK110678MEXT | Japan Society for the Promotion of Science (JSPS) 20K23382MEXT | Japan Society for the Promotion of Science (JSPS) 24K02506NCATS NIH HHS UL1 TR002345NHLBI NIH HHS R01 HL147968NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK104995NIDDK NIH HHS R01 DK117657NIDDK NIH HHS R01 DK126622NIDDK NIH HHS R01 DK131009NIDDK NIH HHS R56 DK115764
Abstract
Nicotinamide adenine dinucleotide (NAD
Indexed as
AdipocytesAgingNADNicotinamide PhosphoribosyltransferaseAnimalsCytokinesEnergy MetabolismFemaleInsulin ResistanceMiceMice, Inbred C57BLMice, KnockoutObesityPhenotypePPAR gammaCytokinesNADNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, mousePPAR gammaadipose tissueaginginsulin resistanceNAD+PPAR-γ
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.