Evidence map›Paper›PMID 38809472›Full record

ArticleEJNMMI research2024

Distribution and predictors of F-18-FDG uptake values of non-malignant cervical lymph nodes in pediatric patients.

Jeremy Godefroy, Raphael Godefroy, Koral Vedder, Yair Altura, Alexandre Chicheportiche, Simona Ben-Haim, Gal Goldstein

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Article in EJNMMI research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jeremy Godefroy *Department of Medical Biophysics and Nuclear Medicine, Hadassah Medical Center, Jerusalem, Israel. jeremyg@hadassah.org.il.ORCID http://orcid.org/0000-0002-6215-772X
Raphael Godefroy *Department of Economics, Universite de Montreal, Montreal, QC, Canada.
Koral VedderFaculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Yair AlturaDepartment of Medical Biophysics and Nuclear Medicine, Hadassah Medical Center, Jerusalem, Israel.
Alexandre ChicheporticheDepartment of Medical Biophysics and Nuclear Medicine, Hadassah Medical Center, Jerusalem, Israel.
Simona Ben-HaimDepartment of Medical Biophysics and Nuclear Medicine, Hadassah Medical Center, Jerusalem, Israel.
Gal GoldsteinThe Dyna and Fala Weinstock Department of Pediatric Hematology-Oncology, Hadassah Hebrew University Medical Center, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundF-18-flurodeoxyglucose (FDG) PET/CT is routinely used for staging, evaluation of response to treatment and follow-up of most pediatric malignancies. Cervical lymph nodes can be involved in some pediatric malignancies, but increased uptake in non-malignant cervical lymph nodes is not exceptional in this population. The aim of the present study is to identify predictors of the maximum uptake in non-malignant cervical lymph nodes in the pediatric population.

methods191 FDG PET/CT studies of pediatric patients without malignant involvement of cervical lymph nodes were retrospectively reviewed. The maximal Standard Uptake Value in the hottest cervical lymph node (SUVmax

resultsIncreased FDG activity in cervical nodes was observed in 136/191 studies (71%). The mean SUVmax

conclusionSUVmax in ipsilateral palatine tonsil is a strong predictor of the maximal uptake value of non-malignant cervical lymph nodes in children. The intensity of uptake in non-malignant cervical lymph nodes is frequently higher than liver uptake in children, and this tendency increases for younger patients. TRIAL WAS REGISTERED: In the internal hospital registry under TRN 0209-22-HMO on date 23.04.2022.

Indexed as

Cervical lymph nodesChildrenDeauville scorePositron emission tomographyTonsil

Identifiers

PMID38809472
PMCPMC11136896

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