Evidence map›Paper›PMID 38809390›Full record

ArticleGeroScience2024

Relationship between skeletal mitochondrial function and digital markers of free-living physical activity in older adults.

Amal A Wanigatunga, Fangyu Liu, Ryan J Dougherty, Karen Bandeen Roche, Jacek K Urbanek, Marta Zampino, Eleanor M Simonsick, Qu Tian, Jennifer A Schrack, Luigi Ferrucci

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GeroScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Rising energetic cost of walking predicts cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amal A WanigatungaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. awaniga1@jhu.edu.ORCID 0000-0002-5763-5184
Fangyu LiuDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ryan J DoughertyCenter On Aging and Health, Johns Hopkins University and Medical Institutions, Baltimore, MD, USA.
Karen Bandeen RocheCenter On Aging and Health, Johns Hopkins University and Medical Institutions, Baltimore, MD, USA.
Jacek K UrbanekCenter On Aging and Health, Johns Hopkins University and Medical Institutions, Baltimore, MD, USA.
Marta ZampinoDepartment of Internal Medicine, University of Maryland, Baltimore, MD, USA.
Eleanor M SimonsickIntramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, USA.
Qu TianIntramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, USA.
Jennifer A SchrackDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Luigi FerrucciIntramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, USA.

Funding

The Baltimore Longitudinal Study Of AgingZIAAG000015 · NIA · NATIONAL INSTITUTE ON AGING · PI SIMONSICK, ELEANOR MARIE · 2009 to 2025
$116.9M
Energy Reserves, Physical Activity, and Alzheimer's Disease in the Baltimore Longitudinal Study of AgingU01AG057545 · NIA · JOHNS HOPKINS UNIVERSITY · PI SCHRACK, JENNIFER ANN · 2017 to 2021
$3.0M
The START trial: a proof-of-concept sedentary reduction program for prefrail older adultsK01AG076967 · NIA · JOHNS HOPKINS UNIVERSITY · PI Amal Asiri Wanigatunga · 2022 to 2026
$651k
Energy expenditure, cognitive function, and biomarker features of Alzheimer's diseaseK01AG080122 · NIA · RUTGERS, THE STATE UNIV OF N.J. · PI Ryan James Dougherty · 2023 to 2026
$501k
Intramural NIH HHS ZIA AG000015NIA NIH HHS K01 AG076967NIA NIH HHS K01AG076967NIA NIH HHS K01 AG080122NIA NIH HHS K01AG080122NIA NIH HHS U01 AG057545NIA NIH HHS U01AG057545NIA NIH HHS ZIAAG000015
6 · The paper itself

Abstract

This study examined the association between in vivo skeletal mitochondrial function and digital free-living physical activity patterns-a measure that summarizes biological, phenotypic, functional, and environmental effects on mobility. Among 459 participants (mean age 68 years; 55% women) in the Baltimore Longitudinal Study of Aging, mitochondrial function was quantified as skeletal muscle oxidative capacity via post-exercise phosphocreatine recovery rate (τ

Indexed as

AccelerometryExerciseAgedAgingBaltimoreFemaleHumansLongitudinal StudiesMagnetic Resonance SpectroscopyMaleMiddle AgedMitochondria, MuscleMuscle, SkeletalPhosphocreatinePhosphocreatineAgingDigital biomarkerMovementMuscle oxidative capacityTechnologyWearables

Identifiers

PMID38809390
PMCPMC11493922

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.