Evidence map›Paper›PMID 38809122›Full record

ReviewAJR. American journal of roentgenology2024

Imaging for Early Detection of Pancreatic Ductal Adenocarcinoma: Updates and Challenges in the Implementation of Screening and Surveillance Programs.

Chenchan Huang, Elizabeth M Hecht, Erik V Soloff, Hina Arif Tiwari, Priya R Bhosale, Anil Dasayam, Samuel J Galgano, Avinash Kambadakone, Naveen M Kulkarni, Ott Le and 5 more

Abstract readReview
In one paragraph

Review in AJR. American journal of roentgenology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Chenchan HuangDepartment of Radiology, NYU Langone Health, 660 First Ave, 3rd Fl, New York, NY 10016.
Elizabeth M HechtDepartment of Radiology, Weill Cornell Medicine, New York, NY.
Erik V SoloffDepartment of Radiology, University of Washington, Seattle, WA.
Hina Arif TiwariDepartment of Radiology, University of Arizona College of Medicine, Banner University Medicine, Tucson, AZ.
Priya R BhosaleDepartment of Radiology, The University of Texas MD Anderson Cancer Center, Bellaire, TX.
Anil DasayamDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Samuel J GalganoDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Avinash KambadakoneDepartment of Radiology, Massachusetts General Hospital, Boston, MA.
Naveen M KulkarniDepartment of Radiology, Medical College of Wisconsin, Milwaukee, WI.
Ott LeDepartment of Radiology, The University of Texas MD Anderson Cancer Center, Bellaire, TX.
Joy LiauDepartment of Radiology, University of California at San Diego, San Diego, CA.
Lyndon LukDepartment of Radiology, Columbia University Medical Center, New York, NY.
Michael H RosenthalDepartment of Radiology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Guillermo P SangsterDepartment of Radiology, OLSU Health Shreveport, Shreveport, LA.
Ajit H GoenkaDepartment of Radiology, Mayo Clinic, Rochester, MN.

Funding

Circulating Biomarker Consortium for Pancreatic Cancer Early DetectionU01CA210171 · NCI · DANA-FARBER CANCER INST · PI Michael H. Rosenthal, Brian Matthew Wolpin · 2016 to 2026
$8.7M
Optimizing Pancreatic Cancer Management with Next Generation Imaging and Liquid BiopsyR01CA256969 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Eric Collisson, Ajit Harishkumar Goenka · 2021 to 2026
$3.1M
Quantitative In Vivo 68Ga-Fibroblast-Activation-Protein-Inhibitors (FAPI)-46 PET Imaging of Cancer-Associated Fibroblasts (CAFs) in Pancreatic Ductal Adenocarcinoma (PDA)R01CA272628 · NCI · MAYO CLINIC ROCHESTER · PI GOENKA, AJIT HARISHKUMAR · 2022 to 2025
$2.5M
NCI NIH HHS R01 CA256969NCI NIH HHS R01 CA272628NCI NIH HHS U01 CA210171
6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive cancers. It has a poor 5-year survival rate of 12%, partly because most cases are diagnosed at advanced stages, precluding curative surgical resection. Early-stage PDA has significantly better prognoses due to increased potential for curative interventions, making early detection of PDA critically important to improved patient outcomes. We examine current and evolving early detection concepts, screening strategies, diagnostic yields among high-risk individuals, controversies, and limitations of standard-of-care imaging.

Indexed as

Carcinoma, Pancreatic DuctalEarly Detection of CancerPancreatic NeoplasmsDiagnostic ImagingHumansMass ScreeningPopulation Surveillanceearly detectionhigh-risk individualsnew-onset diabetespancreatic cancerscreeningsurveillance

Identifiers

PMID38809122
PMCPMC12316096

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.