Evidence map›Paper›PMID 38809008›Full record

Observational studyMicrobiology spectrum2024

An observational study investigating soluble immune checkpoints as indicators of severe COVID-19.

Ricarda Cortés-Vieyra, Sergio Gutiérrez-Castellanos, Anel Gómez-García, Alejandro Bravo-Patiño, Fernando Calderón-Rico, José Daniel Martínez-Sepúlveda, Roberto Ortega-Flores, Francisco Perez-Duran, Luis Enrique Franco-Correa, Alicia Gabriela Zamora-Avilés and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ricarda Cortés-VieyraFacultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Michoacana de San Nicolás de San Nicolás de Hidalgo (UMSNH), Morelia-Zinapécuaro, Mexico.ORCID 0000-0001-9314-6591
Sergio Gutiérrez-CastellanosCentro de Investigación Biomédica de Michoacán, División de Investigación Clínica, Instituto Mexicano del Seguro Social, Morelia, Mexico.
Anel Gómez-GarcíaCentro de Investigación Biomédica de Michoacán, División de Investigación Clínica, Instituto Mexicano del Seguro Social, Morelia, Mexico.
Alejandro Bravo-PatiñoCentro Multidisciplinario de Estudios en Biotecnología de la FMVZ, UMSNH, Morelia-Zinapécuaro, Mexico.ORCID 0000-0001-9897-7634
Fernando Calderón-RicoFacultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Michoacana de San Nicolás de San Nicolás de Hidalgo (UMSNH), Morelia-Zinapécuaro, Mexico.ORCID 0000-0002-6317-816X
José Daniel Martínez-SepúlvedaInstituto de investigaciones Químico Biológicas, UMSNH, Morelia, México.
Roberto Ortega-FloresFacultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Michoacana de San Nicolás de San Nicolás de Hidalgo (UMSNH), Morelia-Zinapécuaro, Mexico.
Francisco Perez-DuranFacultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Michoacana de San Nicolás de San Nicolás de Hidalgo (UMSNH), Morelia-Zinapécuaro, Mexico.ORCID 0000-0001-8732-4793
Luis Enrique Franco-CorreaFacultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Michoacana de San Nicolás de San Nicolás de Hidalgo (UMSNH), Morelia-Zinapécuaro, Mexico.ORCID 0000-0002-9556-4794
Alicia Gabriela Zamora-AvilésFacultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Michoacana de San Nicolás de San Nicolás de Hidalgo (UMSNH), Morelia-Zinapécuaro, Mexico.ORCID 0000-0003-2182-2946
Rosa Elvira Nuñez-AnitaFacultad de Medicina Veterinaria y Zootecnia (FMVZ), Universidad Michoacana de San Nicolás de San Nicolás de Hidalgo (UMSNH), Morelia-Zinapécuaro, Mexico.ORCID 0000-0002-1117-9136

Funding

Consejo Nacional de Ciencia y Tecnología (CONACYT) Fellowship 172265Consejo Nacional de Ciencia y Tecnología (CONACYT) INFR 2015-255010Consejo Nacional de Ciencia y Tecnología (CONACYT) Ref. 317189
6 · The paper itself

Abstract

This study aimed to investigate the immunomodulatory behavior of soluble immune checkpoints (sICPs) and other biomarkers in the pathophysiology of SARS-CoV-2 infection. The study included 59 adult participants, 43 of whom tested positive for SARS-CoV-2. Patients were divided into three cohorts: those with moderate disease (

Indexed as

BiomarkersCOVID-19SARS-CoV-2AdultAgedAged, 80 and overAntibodies, NeutralizingFemaleFibrin Fibrinogen Degradation ProductsHumansImmune Checkpoint ProteinsMaleMiddle AgedSeverity of Illness IndexAntibodies, NeutralizingBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment DImmune Checkpoint ProteinsCOVID-19immune checkpointsobservational studySARS-CoV-2

Identifiers

PMID38809008
PMCPMC11218537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.