Evidence map›Paper›PMID 38809000›Full record

ArticleAntimicrobial agents and chemotherapy2024

Treatment-emergent cefiderocol resistance in carbapenem-resistant

En Huang, Rebekah N Thompson, Sun Hee Moon, Jacob M Keck, Michael S Lowry, Joe Melero, Se-Ran Jun, Eric R Rosenbaum, Ryan K Dare

Abstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. High-Resolution Genomic Surveillance of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Genetic basis of cefiderocol resistance inMicrobiology spectrum · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Successful Treatment of Carbapenem-ResistantInfection and drug resistance · 2026
    Article
  10. Review
  11. Review
  12. Phenotypic and genotypic analysis ofJAC-antimicrobial resistance · 2025
    Article
  13. In vitro activity and resistance mechanisms of novel antimicrobial agents against metallo-β-lactamase producers.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  14. Review
  15. Review
  16. New Agents Are Coming, and So Is the Resistance.Antibiotics (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

En HuangDepartment of Environmental Health Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0009-0000-3647-2454
Rebekah N ThompsonDepartment of Internal Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Sun Hee MoonDepartment of Environmental Health Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Jacob M KeckDepartment of Pharmacy Practice, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Michael S LowryDepartment of Internal Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Joe MeleroDepartment of Pathology and Laboratory Services, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Se-Ran JunDepartment of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0003-2681-3950
Eric R RosenbaumDepartment of Pathology and Laboratory Services, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0002-2770-6578
Ryan K DareDepartment of Internal Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0001-9540-2683

Funding

Pilot Grant ProgramP30GM145393 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI MARK S SMELTZER · 2022 to 2026
$7.6M
NIGMS NIH HHS P30 GM145393University of Arkansas for Medical Sciences VCRI Pioneer Award
6 · The paper itself

Abstract

We report the emergence of cefiderocol resistance in a

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsCarbapenemsCefiderocolCephalosporinsMicrobial Sensitivity TestsAzabicyclo CompoundsBacterial Outer Membrane ProteinsDNA Transposable ElementsDrug Resistance, Multiple, BacterialHumansMaleReceptors, Cell SurfaceSulbactamAnti-Bacterial AgentsAzabicyclo CompoundsBacterial Outer Membrane ProteinsCarbapenemsCefiderocolCephalosporinsDNA Transposable ElementsdurlobactamReceptors, Cell Surfacesiderophore receptorsSulbactamAcinetobacter baumanniicarbapenem resistancecefiderocolISAba36OXA-72sulbactam-durlobactam

Identifiers

PMID38809000
PMCPMC11232405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.