ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2024
A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001-2022.
Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed.
- Hierarchical analysis of unsuccessful tuberculosis treatment among people living with HIV in Brazil using nationwide surveillance data.HIV medicine · 2026Article
- Humanization of care in Primary Health Care: social representations of people with pulmonary tuberculosis.Revista da Escola de Enfermagem da U S P · 2026Article
- Post-tuberculosis lung disease: a joint effort to provide better management in Europe and Brazil.Respiratory research & clinical practice · 2026Article
- Coordinated responses to maintain tuberculosis care amid climate emergencies: challenges and perspectives based on the events of Brazil.BMJ global health · 2025Article
- Trends and clusters of tuberculosis treatment interruption among people experiencing homelessness in Brazil: influence of individual, social and programmatic factors.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025Article
- Trend of epidemiological indicators and factors associated with tuberculosis treatment dropout and death among street people in Brazil: an ecological and cross-sectional study, 2014-2022.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- A critical analysis of the decreasing trends in tuberculosis cure indicators in BrazilAuthors' replyA critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001-2022Evaluation of data quality, timeliness and acceptability of the tuberculosis surveillance system in Brazil's micro-regions Cien Saude.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024Article
- Decreasing trends in tuberculosis cure indicators in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024Article
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6 authors.
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Abstract
objectiveTo analyze the temporal trend of tuberculosis cure indicators in Brazil.
methodsAn ecological time-series study using administrative data of reported cases of the disease nationwide between 2001 and 2022. We estimated cure indicators for each federative unit (FU) considering individuals with pulmonary tuberculosis, tuberculosis-HIV coinfection, and those in tuberculosis retreatment. We used regression models using joinpoint regression for trend analysis, reporting the annual percentage change and the average annual percentage change.
resultsFor the three groups analyzed, we observed heterogeneity in the annual percentage change in the Brazilian FUs, with a predominance of significantly decreasing trends in the cure indicator in most FUs, especially at the end of the time series. When considering national indicators, an average annual percentage change of -0.97% (95% CI: -1.23 to -0.74) was identified for the cure of people with pulmonary tuberculosis, of -1.11% (95% CI: -1.42 to -0.85) for the cure of people with tuberculosis-HIV coinfection, and of -1.44% (95% CI: -1.62 to -1.31) for the cure of people in tuberculosis retreatment.
conclusionsThe decreasing trends of cure indicators in Brazil are concerning and underscore a warning to public authorities, as it points to the possible occurrence of other treatment outcomes, such as treatment discontinuity and death. This finding contradicts current public health care policies and requires urgent strategies aiming to promote follow-up of patients during tuberculosis treatment in Brazil.
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