Evidence map›Paper›PMID 38808522›Full record

ArticleCirculation2024

Cardiovascular Magnetic Resonance Radiomics to Identify Components of the Extracellular Matrix in Dilated Cardiomyopathy.

Shiro Nakamori, Amine Amyar, Ahmed S Fahmy, Long H Ngo, Masaki Ishida, Satoshi Nakamura, Taku Omori, Keishi Moriwaki, Naoki Fujimoto, Kyoko Imanaka-Yoshida and 4 more

Abstract read
In one paragraph

Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  11. Review
  12. A systematic review of machine learning in heart disease prediction.Turkish journal of biology = Turk biyoloji dergisi · 2025
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shiro Nakamori *Departments of Medicine (S. Nakamori, A.A., A.S.F., L.H.N., W.J.M., R.N.), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.ORCID 0000-0001-8165-5268
Amine Amyar *Departments of Medicine (S. Nakamori, A.A., A.S.F., L.H.N., W.J.M., R.N.), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.ORCID 0000-0002-1689-1544
Ahmed S FahmyDepartments of Medicine (S. Nakamori, A.A., A.S.F., L.H.N., W.J.M., R.N.), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Long H NgoDepartments of Medicine (S. Nakamori, A.A., A.S.F., L.H.N., W.J.M., R.N.), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Masaki IshidaRadiology (M.I., S. Nakamura, H.S.), Mie University Graduate School of Medicine, Tsu, Japan.
Satoshi NakamuraRadiology (M.I., S. Nakamura, H.S.), Mie University Graduate School of Medicine, Tsu, Japan.ORCID 0000-0002-9634-9332
Taku OmoriDepartments of Cardiology and Nephrology (S. Nakamori, T.O., K.M., N.F., K.D.), Mie University Graduate School of Medicine, Tsu, Japan.ORCID 0000-0002-3370-9505
Keishi MoriwakiDepartments of Cardiology and Nephrology (S. Nakamori, T.O., K.M., N.F., K.D.), Mie University Graduate School of Medicine, Tsu, Japan.
Naoki FujimotoDepartments of Cardiology and Nephrology (S. Nakamori, T.O., K.M., N.F., K.D.), Mie University Graduate School of Medicine, Tsu, Japan.ORCID 0009-0002-0667-8376
Kyoko Imanaka-YoshidaPathology (K.I.-Y.), Mie University Graduate School of Medicine, Tsu, Japan.
Hajime SakumaRadiology (M.I., S. Nakamura, H.S.), Mie University Graduate School of Medicine, Tsu, Japan.
Kaoru DohiDepartments of Cardiology and Nephrology (S. Nakamori, T.O., K.M., N.F., K.D.), Mie University Graduate School of Medicine, Tsu, Japan.ORCID 0000-0002-5078-6326
Warren J ManningDepartments of Medicine (S. Nakamori, A.A., A.S.F., L.H.N., W.J.M., R.N.), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Reza NezafatDepartments of Medicine (S. Nakamori, A.A., A.S.F., L.H.N., W.J.M., R.N.), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.ORCID 0000-0002-1963-7138

Funding

Cardiovascular MRI Characterization of the Arrhythmogenic Heart in Nonischemic CardiomyopathyR01HL129185 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2015 to 2024
$6.4M
NHLBI NIH HHS R01 HL129185
6 · The paper itself

Abstract

backgroundCurrent cardiovascular magnetic resonance sequences cannot discriminate between different myocardial extracellular space (ECSs), including collagen, noncollagen, and inflammation. We sought to investigate whether cardiovascular magnetic resonance radiomics analysis can distinguish between noncollagen and inflammation from collagen in dilated cardiomyopathy.

methodsWe identified data from 132 patients with dilated cardiomyopathy scheduled for an invasive septal biopsy who underwent cardiovascular magnetic resonance at 3 T. Cardiovascular magnetic resonance imaging protocol included native and postcontrast T

resultsFour histopathological phenotypes were identified: low collagen (n=20), noncollagenous ECS expansion (n=49), mild to moderate collagenous ECS expansion (n=42), and severe collagenous ECS expansion (n=21). Noncollagenous expansion was associated with the highest risk of myocardial inflammation (65%). Although native T

conclusionsRadiomic features extracted from native T

Indexed as

Cardiomyopathy, DilatedExtracellular MatrixAdultAgedBiopsyCollagenFemaleFibrosisHumansMagnetic Resonance ImagingMaleMiddle AgedMyocardiumPrincipal Component AnalysisRadiomicsCollagencardiomyopathy, dilatedhistologymagnetic resonance imagingradiomics

Identifiers

PMID38808522
PMCPMC11216881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.