Evidence map›Paper›PMID 38808464›Full record

ArticleViral immunology2024

Human Immunodeficiency Virus-Human Pegivirus Coinfected Individuals Display Functional Mucosal-Associated Invariant T Cells and Follicular T Cells Irrespective of PD-1 Expression.

Jaisheela Vimali, Yean K Yong, Amudhan Murugesan, Sakthivel Govindaraj, Sivadoss Raju, Pachamuthu Balakrishnan, Marie Larsson, Vijayakumar Velu, Esaki M Shankar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viral immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jaisheela VimaliInfection and Inflammation, Department of Biotechnology, Central University of Tamil Nadu, Thiruvarur, India.
Yean K YongLaboratory Centre, Xiamen University Malaysia, Sepang, Malaysia.
Amudhan MurugesanDepartment of Microbiology, Government Theni Medical College and Hospital, Theni, India.ORCID 0000-0003-4713-2927
Sakthivel GovindarajDepartment of Pathology and Laboratory Medicine, Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, GA, USA.
Sivadoss RajuState Public Health Laboratory, Directorate of Public Health and Preventive Medicine, DMS Campus, Teynampet, India.
Pachamuthu BalakrishnanCentre for Infectious Diseases, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.
Marie LarssonDivision of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Vijayakumar VeluDepartment of Pathology and Laboratory Medicine, Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, GA, USA.
Esaki M ShankarInfection and Inflammation, Department of Biotechnology, Central University of Tamil Nadu, Thiruvarur, India.ORCID 0000-0002-7866-9818

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
NIAID NIH HHS P30 AI050409NIH HHS P51 OD011132
6 · The paper itself

Abstract

Human pegivirus (HPgV) appears to alter the prognosis of HIV disease by modulating T cell homeostasis, chemokine/cytokine production, and T cell activation. In this study, we evaluated if HPgV had any 'favorable' impact on the quantity and quality of T cells in HIV-infected individuals. T cell subsets such as CD4

Indexed as

CoinfectionFlaviviridae InfectionsHIV InfectionsMucosal-Associated Invariant T CellsProgrammed Cell Death 1 ReceptorAdultAntigens, CDAntigens, Differentiation, T-LymphocyteCD4-Positive T-LymphocytesCD69 AntigensCD8-Positive T-LymphocytesCytokinesFemaleHumansLectins, C-TypeLymphocyte ActivationAntigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensCytokinesLectins, C-TypePDCD1 protein, humanProgrammed Cell Death 1 Receptorfollicular T cellsHIV-1MAIT cellsPD-1pegivirusTNF-αviral load

Identifiers

PMID38808464
PMCPMC12054695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.