ArticlePediatric health, medicine and therapeutics2024
Chronic Microvascular Complication of Type 1 Diabetes Mellitus and Its Predictors Among Children with Type 1 Diabetes Mellitus in Ethiopia; A Single Center Experience: Ambi Directional Cohort Study.
Article in Pediatric health, medicine and therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adverse Outcomes and Associated Factors Among Children and Youths With Diabetes Mellitus in East Africa: A Systematic Review and Meta-Analysis.Journal of advanced nursing · 2026Pooled it
- Glycemic control and its associated factors among children and adolescents with type 1 diabetes in Ethiopia: a narrative review.The Pan African medical journal · 2026Review
- Risk of Hypoglycemia and Associated Factors Among In-Hospital Chinese Patients With Latent Autoimmune Diabetes in Adults (LADA): A Multicenter Retrospective Cohort Study.Journal of diabetes research · 2026Article
- Phase angle as an early-warning indicator of glycaemic control in adults with type 1 diabetes mellitus: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Metabolic disorders in young people around the world.Diabetologia · 2025Review
- Distinct complication profiles: a comparative study of Ethiopian and non-Ethiopian adults with type 1 diabetes.Frontiers in endocrinology · 2025Article
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Authors and funding
4 authors.
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Abstract
Introduction: Type 1 diabetes mellitus is the most common pediatric endocrine disorder. Poor glycemic control in diabetes mellitus can result in microvascular complications (retinopathy, neuropathy, and nephropathy). There is no study done in our setting either about prevalence of pediatric type 1 diabetes mellitus or chronic microvascular complication among these patients, which gap this study is expected to fill. Objective: This study aimed to assess the risk and predictors of chronic microvascular complication of type 1 diabetes mellitus among children with diabetes at Haramaya University Hiwot Fana Compressive Specialized Hospital from September 10, 2021 to January 30, 2023. Methods: A hospital-based Ambi directional cohort study was conducted. Survival data are described by follow-up time and Kaplan-Meier graph. To determine predictors associated with chronic microvascular complication we used a Poisson regression optimal model selected using the information criterion. All associations are tested at the 95% confidence level and a reported IRR Results: A total of 124 children with type 1 diabetes mellitus were followed with total 407.5 years risk time. The overall incidence rate of chronic microvascular complication was 83 per 1000 population per year (95% CI: 59-116). The median time for detection of microvascular complication was 7 years after diagnosis. Being male with IRR 1.71 (95% CI: 0. 0.81-3.56), being at pubertal age IRR 1.91 (95% CI: 1.05-3.48), longer diabetes mellitus duration IRR 1.13 (95% CI: 1.07-1.28), and poor glycemic control IRR 1.50 (95% CI: 0.46-4.97) were found to be at higher risk for chronic microvascular complication. Conclusion: There was high incidence of chronic microvascular complication of diabetes mellitus. Being pubertal age group and more than 3 years duration after diagnosis had statistically significant association with complication.
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