Evidence map›Paper›PMID 38807795›Full record

ReviewCureus2024

Fosmanogepix: The Novel Anti-Fungal Agent's Comprehensive Review of in Vitro, in Vivo, and Current Insights From Advancing Clinical Trials.

Ali Almajid, Ali Bazroon, Hashim M Al-Awami, Hassan Albarbari, Ibrahim Alqahtani, Rehab Almutairi, Abbas Alsuwayj, Faiza Alahmadi, Jinan Aljawad, Razan Alnimer and 4 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Pharmacological advances inJournal of enzyme inhibition and medicinal chemistry · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. StudyingPharmaceuticals (Basel, Switzerland) · 2025
    Review
  13. Article
  14. In vitro effects of the new antifungal compound manogepix (APX001) against the three most clinically relevant species of Sporothrix.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  15. Article
  16. Review
  17. Clinical Significance and Therapeutic Challenges ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  18. Review
  19. Review
  20. Managing Invasive Fungal Infections During Allogeneic Hematopoietic Transplantation: A 2025 Update.Mediterranean journal of hematology and infectious diseases · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ali AlmajidInternal Medicine, King Fahad Specialist Hospital, Dammam, SAU.
Ali BazroonInternal Medicine, King Fahad Specialist Hospital, Dammam, SAU.
Hashim M Al-AwamiInternal Medicine, King Fahad Specialist Hospital, Dammam, SAU.
Hassan AlbarbariInternal Medicine, King Fahad Specialist Hospital, Dammam, SAU.
Ibrahim AlqahtaniCollege of Medicine, Arabian Gulf University, Manama, BHR.
Rehab AlmutairiCollege of Medicine, University of Szeged Albert Szent-Györgyi Medical School, Szeged, HUN.
Abbas AlsuwayjCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Faiza AlahmadiCollege of Medicine, Vision College, Riyadh, SAU.
Jinan AljawadCollege of Medicine, University of Szeged Albert Szent-Györgyi Medical School, Szeged, HUN.
Razan AlnimerCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Nawal AsiriCollege of Medicine, King Khalid University, Abha, SAU.
Shouq AlajlaniCollege of Medicine, Umm Al Qura University, Makkah, SAU.
Reem AlshelaliInternal Medicine, King Abdullah Medical Complex, Jeddah, SAU.
Yamama AljishiInternal Medicine, King Fahad Specialist Hospital, Dammam, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fosmanogepix, a prodrug of Manogepix (MGX), is a groundbreaking antifungal agent with broad-spectrum activity against yeasts, including

Indexed as

apx001aspergilluscandidaclinical trialse1210e1211fosmanogepixgwt1.manogepix

Identifiers

PMID38807795
PMCPMC11131969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.