Evidence map›Paper›PMID 38807752›Full record

ArticleReproductive medicine and biology

A new clustering model based on the seminal plasma/serum ratios of multiple trace element concentrations in male patients with subfertility.

Takazo Tanaka, Kosuke Kojo, Yoshiyuki Nagumo, Atsushi Ikeda, Takuya Shimizu, Shunsuke Fujimoto, Toshiyuki Kakinuma, Masahiro Uchida, Tomokazu Kimura, Shuya Kandori and 2 more

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Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Takazo TanakaDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.ORCID https://orcid.org/0000-0002-0370-0323
Kosuke KojoDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.ORCID https://orcid.org/0000-0002-6875-0874
Yoshiyuki NagumoDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.ORCID https://orcid.org/0000-0003-0332-4791
Atsushi IkedaDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.
Takuya ShimizuHealth Care Analysis Center Renatech Co., Ltd. Isehara Kanagawa Japan.ORCID https://orcid.org/0009-0002-9013-3626
Shunsuke FujimotoHealth Care Analysis Center Renatech Co., Ltd. Isehara Kanagawa Japan.
Toshiyuki KakinumaCenter for Human Reproduction International University of Health and Welfare Hospital Nasushiobara Tochigi Japan.ORCID https://orcid.org/0000-0001-7853-4860
Masahiro UchidaDepartment of Urology Tsukuba Gakuen Hospital Tsukuba Ibaraki Japan.ORCID https://orcid.org/0000-0002-3174-4294
Tomokazu KimuraDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.
Shuya KandoriDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.
Hiromitsu NegoroDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.ORCID https://orcid.org/0000-0003-1144-2755
Hiroyuki NishiyamaDepartment of Urology, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate whether seminal plasma (SP)/serum ratios of multiple trace elements (TEs) can classify patients with male subfertility. Methods: SP/serum ratios of 20 TEs (lithium, sodium, magnesium, phosphorus, sulfur, potassium, calcium, manganese, iron, cobalt, copper, zinc, arsenic, selenium, rubidium, strontium, molybdenum, cesium, barium, and thallium) were calculated for healthy volunteers ( Results: The early fraction of volunteers was characterized by lower phosphorus and arsenic and 18 other higher TEs than the subsequent fraction. Cluster analysis classified patients into four distinct clusters, one sharing characteristics with the early fraction and another with the subsequent fraction. One cluster with the early fraction characteristics had significantly lower semen volume and higher pregnancy rates from spontaneous pregnancies or intrauterine insemination. Conclusions: Classification of patients based on SP/serum ratios of multiple TEs represents the dominance of fractions of ejaculation samples.

Indexed as

accessory glandarsenicphosphorussplit ejaculation samplingtrace element

Identifiers

PMID38807752
PMCPMC11131575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.