Evidence map›Paper›PMID 38807091›Full record

Trial reportBMC public health2024

The impact of an innovative community-based peer-led intervention on uptake and coverage of sexual and reproductive health services among adolescents and young people 15-24 years old: results from the Yathu Yathu cluster randomised trial.

Mwelwa Muleba Phiri, Albertus Schaap, Bernadette Hensen, Lucheka Sigande, Melvin Simuyaba, Lawrence Mwenge, Rosemary Zulu-Phiri, Louis Mwape, Sian Floyd, Sarah Fidler and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04060420 (Yathu Yathu), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04060420 naunknown statusnot on this map

Yathu Yathu ("For us, by us"): A Cluster-randomized Trial of Comprehensive Community-based Peer-led Sexual and Reproductive Health Services for Adolescents and Young People Aged 15 to 24 in Lusaka, Zambia

TypeinterventionalSponsorLondon School of Hygiene and Tropical MedicineRan2019 to 2022Enrolled2,000ConditionsHIV Infections, Sexually Transmitted DiseasesArmsComprehensive sexual and reproductive health services
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mwelwa Muleba Phiri *Zambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia. Mwelwa@Zambart.org.zm.
Albertus Schaap *Zambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.
Bernadette HensenSexual Health Unit, Institute of Tropical Medicine, Antwerp, Belgium.
Lucheka SigandeZambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.
Melvin SimuyabaZambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.
Lawrence MwengeZambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.
Rosemary Zulu-PhiriZambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.
Louis MwapeZambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.
Sian FloydDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Sarah FidlerImperial College and Imperial College NIHR BRC, London, UK.
Richard HayesDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Musonda SimwingaZambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.
Helen AylesZambart, Zambart House, UNZA Ridgeway Campus, off Nationalist Road, Lusaka, Zambia.

Funding

Medical Research Council MR/R022216/1
6 · The paper itself

Abstract

backgroundThe Yathu Yathu ("For Us, By Us") cluster-randomized trial (CRT) evaluated a peer-led community-based sexual and reproductive health(SRH) intervention implemented to address persistent barriers to SRH service use among adolescents and young people (AYP). We report the impact of the intervention on coverage of key SRH services among AYP.

methodsThe trial was conducted from Jul 2019-Oct 2021 in two urban communities in Lusaka, Zambia, divided into 20 zones (~ 2350 AYP/zone). Zones were randomly allocated to intervention (N = 10) or control (N = 10) arm. In all zones, a census was conducted and all AYP aged 15-24-years offered participation. The intervention consisted of peer-led community-based hubs providing SRH services; a prevention points card (PPC) system to incentivize and track SRH service use and community engagement. This paper reports on the outcome of coverage (accessing at least one key SRH service), comparing intervention and control arms using PPC data and standard methods of analysis for CRTs.

resultsAmong enumerated AYP, 93.6% (14,872/15,894) consented to participate from intervention zones and 95.1% (14,500/15,255) from control zones. Among those who accepted a PPC, 63.8% (9,493/14,872) accessed at least one key SRH service during the study period in the intervention arm, compared to 5.4% (776/14,500) in the control arm (adjPR 12.3 95%CI 9.3-16.2, p < 0.001).

conclusionsThe Yathu Yathu intervention increased coverage of key SRH services among AYP and reached two-thirds of AYP. These findings demonstrate the potential of providing peer-led community-based SRH services.

trial registrationISRCTN75609016 (11/10/2021), clinicaltrials.gov number NCT04060420 (19/08/2019); retrospectively registered.

Indexed as

Peer GroupReproductive Health ServicesAdolescentCommunity Health ServicesFemaleHumansMalePatient Acceptance of Health CareYoung AdultZambiaAdolescents and young peopleCoverageHIV testingImplementation scienceSexual and reproductive health

Identifiers

PMID38807091
PMCPMC11134624

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.