Evidence map›Paper›PMID 38807037›Full record

ArticleBMC ophthalmology2024

Bilateral optic nerve infiltration and leukemic retinopathy as initial signs of leukemia relapse with central nervous system involvement in an adult: a case report.

Yisai Wang, Ling Zhu, Hongtao Wang, Zhen Li, Ruomeng Bai, Qinghua Wei, Lin Huang, Ying Xu, Songguo Li, Hui Chen

Abstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yisai WangDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Ling ZhuDepartment of haematology, Air Force Medical University, Beijing, China.
Hongtao WangDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Zhen LiDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Ruomeng BaiDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Qinghua WeiDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Lin HuangDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Ying XuDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Songguo LiDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China.
Hui ChenDepartment of Ophthalmology, Peking University Shougang Hospital, 9# Jinyuanzhuang Road, Shijingshan district, Beijing, 100144, China. chenui925@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe a case in which bilateral optic nerve infiltration and leukemic retinopathy were the initial signs of disease relapse in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph CASE PRESENTATION: A 65-year-old Asian female with Ph

conclusionsTo the best of our knowledge, this is the first case report of ALL relapse with CNS involvement presenting as bilateral optic nerve infiltration and leukemic retinopathy in an adult. Hence, we highlight the priority and sensitivity of ophthalmic examinations, as they are noninvasive methods for detecting leukemia relapse.

Indexed as

Leukemic InfiltrationPrecursor Cell Lymphoblastic Leukemia-LymphomaAgedFemaleHumansMagnetic Resonance ImagingNeoplasm Recurrence, LocalOptic NerveRetinal DiseasesVisual AcuityCase reportLeukemic retinopathyOptic nerve infiltrationPhiladelphia chromosome-positive acute lymphoblastic leukemiaRelapse

Identifiers

PMID38807037
PMCPMC11134675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.