Evidence map›Paper›PMID 38806974›Full record

ArticleInfection2024

Challenges in assessing the immunization status of adults in Germany-lessons from a population-based VACCELERATE survey on polio vaccination.

Julia A Nacov, Jannik Stemler, Jon Salmanton-García, Louise M Cremer, Markus Zeitlinger, Patrick W G Mallon, Zoi Dorothea Pana, Heinz-Josef Schmitt, Oliver A Cornely, VACCELERATE Consortium

Abstract read
In one paragraph

Article in Infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julia A NacovFaculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.ORCID http://orcid.org/0000-0002-5327-2937
Jannik StemlerFaculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.ORCID http://orcid.org/0000-0001-9152-2469
Jon Salmanton-GarcíaFaculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.ORCID http://orcid.org/0000-0002-6766-8297
Louise M CremerFaculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.ORCID http://orcid.org/0009-0002-1425-7352
Markus ZeitlingerDepartment of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-1873-3953
Patrick W G MallonSchool of Medicine, University College Dublin, Centre for Experimental Pathogen Host Research, Dublin, Ireland.ORCID http://orcid.org/0000-0002-4337-6222
Zoi Dorothea PanaMedical School, European University Cyprus (EUC), Nicosia, Cyprus.ORCID http://orcid.org/0000-0002-5893-1081
Heinz-Josef SchmittFaculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.ORCID http://orcid.org/0000-0002-0378-5697
Oliver A CornelyFaculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany. oliver.cornely@uk-koeln.de.ORCID http://orcid.org/0000-0001-9599-3137
VACCELERATE Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeConsidering the re-emergence of poliomyelitis (PM) in non-endemic regions, it becomes apparent that vaccine preventable diseases can rapidly develop epi- or even pandemic potential. Evaluation of the current vaccination status is required to inform patients, health care providers and policy makers about vaccination gaps.

methodsBetween October 28 2022 and November 23 2022, 5,989 adults from the VACCELEREATE Volunteer Registry completed an electronic case report form on their previous PM vaccine doses including number, types/-valencies and the time of administration based on their vaccination records. A uni-/multivariable regression analysis was performed to assess associations in participant characteristics and immunization status.

resultsAmong German volunteers (n = 5,449), complete PM immunization schedule was found in 1,981 (36%) participants. Uncertain immunization, due to unknown previous PM vaccination (n = 313, 6%), number of doses (n = 497, 9%), types/-valencies (n = 1,233, 23%) or incoherent immunization schedule (n = 149, 3%) was found in 40% (n = 2,192). Out of 1,276 (23%) participants who reported an incomplete immunization schedule, 62 (1%) never received any PM vaccine. A total of 5,074 (93%) volunteers reported having been vaccinated at least once and 2,087 (38%) indicated that they received vaccination within the last ten years. Female sex, younger age, as well as availability of first vaccination record were characteristics significantly associated with complete immunization (p < 0.001).

conclusionFull PM immunization schedule was low and status frequently classified as uncertain due to lack of details on administered doses. There is an obviousneed for improved recording to enable long-term access to detailed vaccination history in the absence of a centralized immunization register.

Indexed as

PoliomyelitisVaccinationAdolescentAdultAgedFemaleGermanyHumansImmunization ScheduleMaleMiddle AgedPoliovirus VaccinesSurveys and QuestionnairesVaccination CoverageYoung AdultPoliovirus VaccinesInfection controlPandemic preparednessPublic healthSurveillanceVaccination coverageVaccine preventable

Identifiers

PMID38806974
PMCPMC11289296

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.