Evidence map›Paper›PMID 38806950›Full record

ReviewJournal of imaging informatics in medicine2024

Enhancing AI Research for Breast Cancer: A Comprehensive Review of Tumor-Infiltrating Lymphocyte Datasets.

Alessio Fiorin, Carlos López Pablo, Marylène Lejeune, Ameer Hamza Siraj, Vincenzo Della Mea

Abstract readReview
In one paragraph

Review in Journal of imaging informatics in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Targeting low-risk triple-negative breast cancer: a review on de-escalation strategies for a new era.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2025
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alessio Fiorin *Oncological Pathology and Bioinformatics Research Group, Institut d'Investigació Sanitària Pere Virgili (IISPV), C/Esplanetes no 14, 43500, Tortosa, Spain. alessio.fiorin@estudiants.urv.cat.ORCID 0009-0002-0315-1085
Carlos López Pablo *Oncological Pathology and Bioinformatics Research Group, Institut d'Investigació Sanitària Pere Virgili (IISPV), C/Esplanetes no 14, 43500, Tortosa, Spain. clopezp.ebre.ics@gencat.cat.ORCID 0000-0003-1248-3065
Marylène LejeuneOncological Pathology and Bioinformatics Research Group, Institut d'Investigació Sanitària Pere Virgili (IISPV), C/Esplanetes no 14, 43500, Tortosa, Spain.ORCID 0000-0001-8441-9404
Ameer Hamza SirajDepartment of Mathematics, Computer Science and Physics, University of Udine, Udine, Italy.ORCID 0009-0008-6443-9203
Vincenzo Della MeaDepartment of Mathematics, Computer Science and Physics, University of Udine, Udine, Italy.ORCID 0000-0002-0144-3802

Funding

HORIZON-MSCA-2021-DN-01-01 101073222Proyectos Estratégicos Orientados a la Transición Ecol ógica y a la Transición Digital TED2021-130081B-C22
6 · The paper itself

Abstract

The field of immunology is fundamental to our understanding of the intricate dynamics of the tumor microenvironment. In particular, tumor-infiltrating lymphocyte (TIL) assessment emerges as essential aspect in breast cancer cases. To gain comprehensive insights, the quantification of TILs through computer-assisted pathology (CAP) tools has become a prominent approach, employing advanced artificial intelligence models based on deep learning techniques. The successful recognition of TILs requires the models to be trained, a process that demands access to annotated datasets. Unfortunately, this task is hampered not only by the scarcity of such datasets, but also by the time-consuming nature of the annotation phase required to create them. Our review endeavors to examine publicly accessible datasets pertaining to the TIL domain and thereby become a valuable resource for the TIL community. The overall aim of the present review is thus to make it easier to train and validate current and upcoming CAP tools for TIL assessment by inspecting and evaluating existing publicly available online datasets.

Indexed as

Breast NeoplasmsLymphocytes, Tumor-InfiltratingArtificial IntelligenceDeep LearningFemaleHumansTumor MicroenvironmentBreast CancerComputer VisionDatasetsDeep LearningImmunologyTIL

Identifiers

PMID38806950
PMCPMC11612116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.