Evidence map›Paper›PMID 38806755›Full record

SynthesisNeurosurgical review2024

Predictors of early and late postoperative seizures in meningioma patients: a systematic review and meta-analysis.

Alina Ghazou, Ahmed Yassin, Ahmed S Aljabali, Yazan S Al-Zamer, Mohmmad Alawajneh, Ashaar Al-Akhras, Majd M AlBarakat, Shaden Tashtoush, Omar Shammout, Sami S Al-Horani and 3 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alina GhazouFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan. aaghazou19@med.just.edu.jo.
Ahmed YassinDepartment of Neurology, Jordan University of Science and Technology, Irbid, Jordan.
Ahmed S AljabaliFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Yazan S Al-ZamerFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Mohmmad AlawajnehFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Ashaar Al-AkhrasFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Majd M AlBarakatFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Shaden TashtoushFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Omar ShammoutFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Sami S Al-HoraniFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Eman E JarrahFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Obada AbabnehFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Amer JaradatDepartment of Neurosurgery, Jordan University of Science and Technology, Irbid, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meningioma is the most common type of primary brain tumor which presents with a variety of neurological manifestations. Surgical resection tends to be the preferred treatment. The occurrence of seizures after resection is common, which occur either early, within seven days of operation, or late. Our meta-analysis investigated the possible predictors of early and late postoperative seizures. We assessed the relevant observational studies on predictors of postoperative seizures published in PubMed, Scopus, and Web of Science from January 2000 to September 2022, and those that met inclusion criteria were included. We calculated the association between potential predicting factors and postoperative seizures, odds ratios (ORs) with 95% confidence intervals (CIs) applying either random or fixed-effect models. The early and late postoperative seizures were evaluated individually. Thirteen observational studies involving 4176 patients were included. Seizures occurred in 250 (6%) and 584 (14%) patients, respectively, in the early and late postoperative phases. Shared predictors for early and late seizures included tumors involving the motor cortex (OR = 2.7; 95% CI: 1.67-4.38, OR = 2.46; 95% CI: 1.68-3.61), postoperative neurological deficit (OR = 4.68; 95% CI: 2.67-8.22, OR = 2.01; 95% CI: 1.39-2.92), and preoperative seizures (OR = 2.52; 95% CI: 1.82-3.49, OR = 4.35; 95% CI: 3.29-5.75). Peritumoral edema (OR = 1.99; 95% CI: 1.49-2.64) was a significant factor only among late postoperative seizure patients while surgical complications (OR = 3.77; 95% CI: 2.39-5.93) was a significant factor solely for early postoperative seizures. Meningioma patients commonly experience early and late postoperative seizures. Identifying predictors of postoperative seizures is essential to diagnose and manage them effectively.

Indexed as

Meningeal NeoplasmsMeningiomaPostoperative ComplicationsSeizuresHumansNeurosurgical ProceduresEarlyLateMeningiomaPostoperativeSeizures

Identifiers

PMID38806755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.