Evidence map›Paper›PMID 38806671›Full record

ArticleNature microbiology2024

Mycobacterium tuberculosis produces D-serine under hypoxia to limit CD8

Hongyu Cheng, Zhe Ji, Yang Wang, Shenzhi Li, Tianqi Tang, Fei Wang, Cheng Peng, Xiangyang Wu, Yuanna Cheng, Zhonghua Liu and 14 more

Abstract read
In one paragraph

Article in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  11. Deletion ofFrontiers in microbiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Hongyu Cheng *Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Zhe Ji *Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Yang WangDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, PR China.
Shenzhi LiDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, PR China.
Tianqi TangDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, PR China.
Fei WangDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, PR China.
Cheng PengDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, PR China.ORCID http://orcid.org/0009-0008-5624-4393
Xiangyang WuClinical and Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Yuanna ChengDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, PR China.
Zhonghua LiuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Mingtong MaDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, PR China.
Jie WangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Xiaochen HuangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Lin WangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Lianhua QinShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Haipeng LiuClinical and Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.ORCID http://orcid.org/0000-0002-3338-6291
Jianxia ChenClinical and Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Ruijuan ZhengShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China.
Carl G FengImmunology and Host Defense Group, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-4301-4640
Xia CaiBiosafety Level 3 Laboratory, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Di QuBiosafety Level 3 Laboratory, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Lilin YeInstitute of Immunology, Third Military Medical University, Chongqing, P. R. China. yelilinlcmv@tmmu.edu.cn.
Hua YangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China. yanghua97065@163.com.
Baoxue GeShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, P. R. China. gebaoxue@sibs.ac.cn.ORCID http://orcid.org/0000-0002-4086-8299

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32188101National Natural Science Foundation of China (National Science Foundation of China) 82270006
6 · The paper itself

Abstract

Adaptation to hypoxia is a major challenge for the survival of Mycobacterium tuberculosis (Mtb) in vivo. Interferon (IFN)-γ-producing CD8

Indexed as

CD8-Positive T-LymphocytesInterferon-gammaMacrophagesMycobacterium tuberculosisSerineTuberculosisAnimalsBacterial ProteinsFemaleHost-Pathogen InteractionsHypoxiaMechanistic Target of Rapamycin Complex 1MiceMice, Inbred C57BLTransaminasesBacterial ProteinsInterferon-gammaMechanistic Target of Rapamycin Complex 1phosphoserine aminotransferaseSerineTransaminases

Identifiers

PMID38806671
PMCPMC11222154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.