ReviewPediatric research2024
Brain health in preterm infants: importance of early-life pain and analgesia exposure.
Review in Pediatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Reconsidering transcutaneous bilirubinometry for management of neonatal hyperbilirubinemia: is it time for change?Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Early-life fentanyl exposure, microbiome-brain axis and neurodevelopment.Pediatric research · 2026Article
- Sweeter recovery, less intravenous fluids: a NICU quality improvement initiative for managing neonatal hypoglycemia.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Neuroprognostication in infants born preterm at the limits of viability: assessment under uncertainty.Pediatric research · 2026Review
- [Anesthesia in neonates and preterm infants : Current knowledge on ventilation, circulation and transfusion].Die Anaesthesiologie · 2026Review
- Beyond the face: advancing multimodal AI for neonatal pain assessment.Pediatric research · 2026Article
- Through Parents' Eyes: Reframing Neonatal Pain Assessment Through Lived Experience.Paediatric & neonatal pain · 2026Article
- Population-Based Cohort Study for Development of National Retinopathy of Prematurity Screening Criteria.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Sweet relief or lasting impacts? Review of neonatal pain and sucrose in developing rodents.Pain reports · 2025Article
- Burden of "Pokes" in Newborns With Hypoglycemia Who Require IV Dextrose.Hospital pediatrics · 2025Article
- Analgesia and sedation increases bronchopulmonary dysplasia risk without significant neurodevelopmental impairment in very preterm infants.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Everyday" exposures in the neonatal period, such as pain, may impact brain health in preterm infants. Specifically, greater exposure to painful procedures in the initial weeks after birth have been related to abnormalities in brain maturation and growth and poorer neurodevelopmental outcomes in preterm infants. Despite an increasing focus on the importance of treating pain in preterm infants, there is a lack of consensus of optimal approaches to managing pain in this population. This may be due to recent findings suggesting that commonly used analgesic and sedative medications in preterm infants may also have adverse effects of brain maturation and neurodevelopmental outcomes. This review provides an overview of potential impacts of pain and analgesia exposure on preterm brain health while highlighting research areas in need of additional investigations for the development of optimal pain management strategies in this population.
Indexed as
Identifiers
38806664What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.