ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2024
Long-term consequences of urinary tract infection in childhood: an electronic population-based cohort study in Welsh primary and secondary care.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Procalcitonin in predicting acute kidney damage in children with initial febrile urinary tract infection: a retrospective study.Translational pediatrics · 2026Article
- Multifactorial chronic kidney disease and the kidney capacity-workload balance.Nature reviews. Nephrology · 2026Review
- An observational study on multidrug resistance in pediatric patients with urinary tract infections.Naunyn-Schmiedeberg's archives of pharmacology · 2026Observational
- Epidemiological profile of urinary tract infections in children before and during the COVID-19 pandemic: an observational study.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026Observational
- Urinary Tract Infection in Children: An Up-To-Date Study.Biomedicines · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildhood urinary tract infection (UTI) can cause renal scarring, and possibly hypertension, chronic kidney disease (CKD), and end-stage renal failure (ESRF). Previous studies have focused on selected populations, with severe illness or underlying risk factors. The risk for most children with UTI is unclear.
aimTo examine the association between childhood UTI and outcomes in an unselected population of children. DESIGN AND
settingA retrospective population-based cohort study using linked GP, hospital, and microbiology records in Wales, UK.
methodParticipants were all children born in 2005-2009, with follow-up until 31 December 2017. The exposure was microbiologically confirmed UTI before the age of 5 years. The key outcome measures were renal scarring, hypertension, CKD, and ESRF.
resultsIn total, 159 201 children were included; 77 524 (48.7%) were female and 7% (
conclusionThe prevalence of renal scarring in an unselected population of children with UTI is low. Without underlying risk factors, UTI is not associated with CKD, hypertension, or ESRF by the age of 10 years. Further research with systematic scanning of children's kidneys, including those with less severe UTI and without UTI, is needed to increase the certainty of these results, as most children are not scanned. Longer follow-up is needed to establish if UTI, without additional risk factors, is associated with hypertension, CKD, or ESRF later in life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.