Evidence map›Paper›PMID 38806166›Full record

ArticleACS applied materials & interfaces2024

A Nanoplasmonic Assay for Point-of-Care Detection of Mannose-Binding Lectin in Human Serum.

Alessia Pancaro, Michal Szymonik, Patricia Perez Schmidt, Gizem Erol, Africa Garcia Barrientos, Laura Polito, Marco Gobbi, Sam Duwé, Jelle Hendrix, Inge Nelissen

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessia PancaroHealth Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, Mol 2400, Belgium.ORCID 0000-0003-4586-3531
Michal SzymonikHealth Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, Mol 2400, Belgium.
Patricia Perez SchmidtIstituto di Scienze e Tecnologie Chimiche "Giulio Natta", SCITEC-CNR, G, Fantoli 16/15, Milan 20138, Italy.
Gizem ErolIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Mario Negri 2 20156, Milan, Italy.
Africa Garcia BarrientosMidatech Pharma PLC, Oddfellows House, 19 Newport Road, Cardiff CF24 0AA, U.K.
Laura PolitoIstituto di Scienze e Tecnologie Chimiche "Giulio Natta", SCITEC-CNR, G, Fantoli 16/15, Milan 20138, Italy.ORCID 0000-0002-7756-2365
Marco GobbiIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Mario Negri 2 20156, Milan, Italy.ORCID 0000-0003-1014-6225
Sam DuwéAdvanced Optical Microscopy Centre, Biomedical Research Institute, Hasselt University, Agoralaan C, Diepenbeek 3590, Belgium.ORCID 0000-0003-3768-1877
Jelle HendrixDynamic Bioimaging Lab, Biomedical Research Institute, Hasselt University, Agoralaan C, Diepenbeek 3590, Belgium.ORCID 0000-0001-5731-1297
Inge NelissenHealth Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, Mol 2400, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mannose-binding lectin (MBL) activates the complement system lectin pathway and subsequent inflammatory mechanisms. The incidence and outcome of many human diseases, such as brain ischemia and infections, are associated with and influenced by the activity and serum concentrations of MBL in body fluids. To quantify MBL levels, tests based on ELISA are used, requiring several incubation and washing steps and lengthy turnaround times. Here, we aimed to develop a nanoplasmonic assay for direct MBL detection in human serum at the point of care. Our assay is based on gold nanorods (GNRs) functionalized with mannose (Man-GNRs)

Indexed as

Biosensing TechniquesGoldMannose-Binding LectinPoint-of-Care SystemsHumansMannoseMetal NanoparticlesNanotubesGoldMannoseMannose-Binding Lectingold nanorodslabel-free biosensorlocalized surface plasmon resonancemannose-binding lectinmannose surface functionalization

Identifiers

PMID38806166
PMCPMC11181273

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.