Evidence map›Paper›PMID 38805357›Full record

ArticleBJS open2024

Robotic, transanal, and laparoscopic total mesorectal excision for locally advanced mid/low rectal cancer: European multicentre, propensity score-matched study.

Nicola de'Angelis, Francesco Marchegiani, Aleix Martínez-Pérez, Alberto Biondi, Salvatore Pucciarelli, Carlo Alberto Schena, Gianluca Pellino, Miquel Kraft, Annabel S van Lieshout, Luca Morelli and 8 more

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in BJS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
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  10. Short-term outcomes of laparoscopic-assisted transanalWorld journal of gastrointestinal surgery · 2026
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  13. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Nicola de'AngelisUnit of Robotic and Minimally Invasive Digestive Surgery, Department of Surgery, Ferrara University Hospital, Ferrara (Cona), Italy.ORCID 0000-0002-1211-4916
Francesco MarchegianiUnit of Colorectal and Digestive Surgery, DIGEST Department, Beaujon University Hospital (AP-HP), Clichy, France.ORCID 0000-0002-5312-8054
Aleix Martínez-PérezUnit of Colorectal Surgery, Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain.
Alberto BiondiGeneral Surgery Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-2470-7858
Salvatore PucciarelliGeneral Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.ORCID 0000-0001-5289-9925
Carlo Alberto SchenaUnit of Robotic and Minimally Invasive Digestive Surgery, Department of Surgery, Ferrara University Hospital, Ferrara (Cona), Italy.ORCID 0000-0003-1136-1103
Gianluca PellinoUnit of Colorectal Surgery, Department of General and Digestive Surgery, University Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain.ORCID 0000-0002-8322-6421
Miquel KraftUnit of Colorectal Surgery, Department of General and Digestive Surgery, University Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain.
Annabel S van LieshoutDepartment of Surgery, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Luca MorelliGeneral Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Alain ValverdeDepartment of Digestive Surgery, Groupe Hospitalier Diaconesses, Croix Saint-Simon, Paris, France.
Renato Micelli LupinacciDepartment of Digestive Surgery, Groupe Hospitalier Diaconesses, Croix Saint-Simon, Paris, France.
Segundo A Gómez-AbrilUnit of Colorectal Surgery, Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain.
Roberto PersianiGeneral Surgery Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Jurriaan B TuynmanDepartment of Surgery, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Eloy Espin-BasanyUnit of Colorectal Surgery, Department of General and Digestive Surgery, University Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain.
Frederic RisService of Abdominal Surgery, Geneva University Hospitals and Medical School, Geneva, Switzerland.
European MRI and Rectal Cancer Surgery (EuMaRCS) Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal mesorectal excision (TME) is the standard surgery for low/mid locally advanced rectal cancer. The aim of this study was to compare three minimally invasive surgical approaches for TME with primary anastomosis (laparoscopic TME, robotic TME, and transanal TME).

methodsRecords of patients undergoing laparoscopic TME, robotic TME, or transanal TME between 2013 and 2022 according to standardized techniques in expert centres contributing to the European MRI and Rectal Cancer Surgery III (EuMaRCS-III) database were analysed. Propensity score matching was applied to compare the three groups with respect to the complication rate (primary outcome), conversion rate, postoperative recovery, and survival.

resultsA total of 468 patients (mean(s.d.) age of 64.1(11) years) were included; 190 (40.6%) patients underwent laparoscopic TME, 141 (30.1%) patients underwent robotic TME, and 137 (29.3%) patients underwent transanal TME. Comparative analyses after propensity score matching demonstrated a higher rate of postoperative complications for laparoscopic TME compared with both robotic TME (OR 1.80, 95% c.i. 1.11-2.91) and transanal TME (OR 2.87, 95% c.i. 1.72-4.80). Robotic TME was associated with a lower rate of grade A anastomotic leakage (2%) compared with both laparoscopic TME (8.8%) and transanal TME (8.1%) (P = 0.031). Robotic TME (1.4%) and transanal TME (0.7%) were both associated with a lower conversion rate to open surgery compared with laparoscopic TME (8.8%) (P < 0.001). Time to flatus and duration of hospital stay were shorter for patients treated with transanal TME (P = 0.003 and 0.001 respectively). There were no differences in operating time, intraoperative complications, blood loss, mortality, readmission, R0 resection, or survival.

conclusionIn this multicentre, retrospective, propensity score-matched, cohort study of patients with locally advanced rectal cancer, newer minimally invasive approaches (robotic TME and transanal TME) demonstrated improved outcomes compared with laparoscopic TME.

Indexed as

LaparoscopyPostoperative ComplicationsPropensity ScoreRectal NeoplasmsRobotic Surgical ProceduresAgedEuropeFemaleHumansLength of StayMaleMiddle AgedProctectomyRectumRetrospective StudiesTransanal Endoscopic Surgery

Identifiers

PMID38805357
PMCPMC11132137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.