ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024
Considerations for the use of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) in cross-country comparisons of cognitive aging and dementia.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Dual sensory loss and cognitive performance among older adults in India.Journal of Alzheimer's disease : JAD · 2026Article
- Socioeconomic and clinical predictors of all-cause mortality among older adults in India from 2017 to 2024: the importance of cognitive health and dementia.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- The measurement of cognition in large-scale cross-national surveys: lessons from the Health and Retirement Study International Network of Studies and the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Recommended contents for a longitudinal, population-representative study of health, retirement, and aging.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Experience with an online positive psychology intervention for caregivers of people with Alzheimer's disease: an interpretative phenomenological analysis.International journal of qualitative studies on health and well-being · 2025Article
- Estimating cognitive decline in longitudinal studies with high mortality and a long interwave period: A comparison of approaches and considerations around integrating end-of-life interview data.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Validity and reliability of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for dementia assessment in rural South Africa.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Observational
- Unraveling the role of proteins in dementia: insights from two UK cohorts with causal evidence.Brain communications · 2025Article
- Considerations for the use of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) in cross-country comparisons of cognitive aging and dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Decomposing Racial and Ethnic Disparities in Risk and Protective Factors of Dementia in the U.S.Clinical gerontologistArticle
- Racial and ethnic differences in informant reports of cognitive impairment.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Abstract
introductionInformant reports are a critical component of dementia diagnoses, but the comparability of informant reports across countries is not well understood.
methodsWe compared the performance of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) using population-representative surveys in the United States (N = 3183), England (N = 1050), and India (N = 4047).
resultsAnalyses of regression splines and comparisons of model fit showed strong associations between IQCODE and objective cognition at low cognitive functioning in the United States and England; in India, the association was weaker but consistent over the range of cognition. Associations between IQCODE score and informant generation (analysis of variance [ANOVA] p = 0.001), caregiver status (p < 0.001), and years known by the informant (p = 0.015) were different across countries after adjusting for objective cognition. DISCUSSION: In India, the IQCODE was less sensitive to impairments at the lowest levels of cognitive functioning. Country-specific adjustments to IQCODE scoring based on informant characteristics may improve cross-national comparisons. HIGHLIGHTS: Associations between IQCODE and cognitive testing were similar in the United States and England but differed in India. In India, the IQCODE may be less sensitive to impairments among those with low cognition and no education. Informant characteristics may differentially impact informant reports of decline across countries. Adjustments or culturally sensitive adaptations may improve cross-national comparability.
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