Evidence map›Paper›PMID 38805284›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2.

Shiyu Liang, Aijun Liu, Yezhou Liu, Fuxing Wang, Youli Zhou, Yuanzhengyang Long, Tao Wang, Zheng Liu, Ruobing Ren, Richard D Ye

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shiyu Liang *Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.ORCID 0009-0002-0261-3727
Aijun Liu *Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.
Yezhou LiuKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.ORCID 0000-0001-7575-8260
Fuxing WangKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.ORCID 0009-0005-0812-183X
Youli ZhouKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.
Yuanzhengyang LongKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.ORCID 0009-0009-7909-3230
Tao WangInstitute of Infectious Diseases, Shenzhen Bay Laboratory, Guangming District, Shenzhen 518132, China.
Zheng LiuKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.ORCID 0000-0002-3538-9349
Ruobing RenShanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai 200438, China.ORCID 0000-0003-4517-7216
Richard D YeKobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.ORCID 0000-0002-2164-5620

Funding

China Postdoctoral Science Foundation (China Postdoctoral Foundation Project) 2022M713049MOST | National Key Research and Development Program of China (NKPs) 2019YFA0906003MOST | National Natural Science Foundation of China (NSFC) 32070950Science, Technology and Innovation Commission of Shenzhen Municipality () GXWD20201231105722002- 20200831175432002Shenzhen Municipal Science and Technology Innovation Council | Shenzhen Science and Technology Innovation Program () RCBS20221008093330067
6 · The paper itself

Abstract

Essential for reactive oxygen species (EROS) protein is a recently identified molecular chaperone of NOX2 (gp91

Indexed as

Cryoelectron MicroscopyNADPH Oxidase 2NADPH OxidasesPhagocytesBinding SitesGranulomatous Disease, ChronicHumansModels, MolecularProtein BindingReactive Oxygen SpeciesCYBB protein, humanNADPH Oxidase 2NADPH OxidasesReactive Oxygen Specieschronic granulomatous diseaseEROSNADPH oxidaseneutrophilsNOX2

Identifiers

PMID38805284
PMCPMC11161758

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.