Evidence map›Paper›PMID 38805132›Full record

ArticleJournal of fluorescence2025

Pyridine-2,6-Dicarboxylic Acid As a Facile and Highly Selective "Turn-Off" Fluorimetric Chemosensor for Detection of Cu (II) Ions in Aqueous Media.

Javed Hussain Shah, Shahzad Sharif, Muhammad Shahbaz, Bilal Riaz, Sundas Shahzad, Onur Şahin, Khurram Shahzad Munawar, Hijaz Ahmad, Essam A Al-Ammar

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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Turn-off Fluorimetric Detection of FeJournal of fluorescence · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Javed Hussain ShahMaterials Chemistry Laboratory, Institute of Chemical Sciences, Government College University Lahore, Lahore, 54000, Pakistan.
Shahzad SharifMaterials Chemistry Laboratory, Institute of Chemical Sciences, Government College University Lahore, Lahore, 54000, Pakistan. mssharif@gcu.edu.pk.
Muhammad ShahbazMaterials Chemistry Laboratory, Institute of Chemical Sciences, Government College University Lahore, Lahore, 54000, Pakistan.
Bilal RiazMaterials Chemistry Laboratory, Institute of Chemical Sciences, Government College University Lahore, Lahore, 54000, Pakistan.
Sundas ShahzadMaterials Chemistry Laboratory, Institute of Chemical Sciences, Government College University Lahore, Lahore, 54000, Pakistan.
Onur ŞahinDepartment of Occupat Health & Safety, Faculty of Health Sciences, Sinop University, TR-57000, Sinop, Turkey.
Khurram Shahzad MunawarDepartment of Chemistry, University of Mianwali, Mianwali, Pakistan.
Hijaz AhmadSection of Mathematics, International Telematic University Uninettuno, Corso Vittorio Emanuele II, 39, 00186, Rome, Italy.
Essam A Al-AmmarDepartment of Electrical Engineering, College of Engineering, King Saud University, P.O. Box 800, 11421, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copper metal is third most abundant trace element in human body. Determination of Cu (II) ions is a burning topic in field of environment protection and food safety because of its significant impact on ecosystem. In this study, 2,6-pyridine dicarboxylic acid (PDA) has been explored as "turn-off" florescent probe for florescent detection of Cu (II) ions. This sensor showed highly selective complexing ability towards Cu (II) ions. Addition of aqueous solution of Cu (II) ions remarkably quenched the fluorescence intensity of PDA while, on contrary, there was no any prominent fluorescence quenching interference on addition of various metal ions. The binding mode of PDA and Cu (II) ions was determined as stoichiometry of 1:1 and it was further confirmed by single crystal XRD analysis. Mechanisms of static and dynamic quenching were confirmed by stern-volmer plot. Limit of detection (LOD) and limit of quantification (LOQ) for Cu (II) ions was calculated as 3.6 µM and 1.23 µM respectively, which is far below the acceptable value (31.5µM) according to the World Health Organization. The use of the sensor for detection of Cu (II) ions in real samples in aqueous media was also performed.

Indexed as

Cu (II) ionsJob’s plotPyridine-2,6-dicarboxylic acidTurn off fluorescent probeXRD-structure

Identifiers

PMID38805132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.