Evidence map›Paper›PMID 38805069›Full record

Trial reportLasers in medical science2024

Dose-response and efficacy of 904 nm photobiomodulation on diabetic foot ulcers healing: a randomized controlled trial.

Vinicius Saura Cardoso, Pedro Renan de Souza Lima da Silveira, Cristiana Maria Dos Santos, Mariana Bezerra Miranda, Ana Carolina Silva Barros, Lorena Coelho Veloso, Alessandra Tanuri Magalhães, Rebeca Barbosa da Rocha, Fuad Ahmad Hazime

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04246814 (Effect of Low-level Laser Therapy in the Treatment of Diabetic Foot Ulcers), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04246814 nacompletednot on this map

Effect of Low-level Laser Therapy in the Treatment of Diabetic Foot Ulcers: a Double-blind Randomized Controlled Trial

TypeinterventionalSponsorFederal University of PiauiRan2019 to 2023Enrolled80ConditionsDiabetic Foot Ulcer, Diabetic FootArmsLG1, LG2, LG3, CC, Dressing
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vinicius Saura CardosoCenter of Medical Specialties, Parnaíba, Piauí, Brazil. vscfisio@ufdpar.edu.br.ORCID http://orcid.org/0000-0003-0269-7473
Pedro Renan de Souza Lima da SilveiraCenter of Medical Specialties, Parnaíba, Piauí, Brazil.
Cristiana Maria Dos SantosCenter of Medical Specialties, Parnaíba, Piauí, Brazil.
Mariana Bezerra MirandaCenter of Medical Specialties, Parnaíba, Piauí, Brazil.
Ana Carolina Silva BarrosCenter of Medical Specialties, Parnaíba, Piauí, Brazil.
Lorena Coelho VelosoCenter of Medical Specialties, Parnaíba, Piauí, Brazil.
Alessandra Tanuri MagalhãesCenter of Medical Specialties, Parnaíba, Piauí, Brazil.
Rebeca Barbosa da RochaCenter of Medical Specialties, Parnaíba, Piauí, Brazil.
Fuad Ahmad HazimePostgraduate program in Biomedical Sciences, Parnaíba Delta Federal University (UFDPar), Parnaíba, Piauí, Brazil.

Funding

Fundação de Amparo à Pesquisa do Estado do Piauí Fundação de Amparo à Pesquisa do Estado do Piauí
6 · The paper itself

Abstract

purposeThis study aimed to examine the impact of a 904 nm photobiomodulation (PBM) on diabetic ulcers using varying dosages.

methodsThe study was a randomized, double-blind, placebo-controlled clinical trial that compared treatments using PBM (GaAs 904 nm 30w) with three different energy densities (4 J/cm

resultsGaAs 904 nm PBM yielded a clinically and significant ulcer size rate reduction of diabetic foot ulcers, independently of energy density range (p < 0.05). However, 10 J/cm² had 60% of completely healed ulcers and the highest proportion of patients reaching 50% of ulcer reduction rate after 5 weeks of treatment. In addition, only 10 J/cm² showed a significant difference between control group after a 10-week follow-up (p < 0.05).

conclusionGaAs 904 nm PBM was effective in treating diabetic foot ulcers in this study and a dosage of 10 J/cm², after a 10-week follow-up, proved to be the most effective compared to the other groups. CLINICAL TRIAL REGISTRATION NUMBER: NCT04246814.

Indexed as

Diabetic FootLow-Level Light TherapyWound HealingAdultAgedDose-Response Relationship, RadiationDouble-Blind MethodFemaleHumansMaleMiddle AgedTreatment OutcomeDiabetic Foot UlcersGaAs 904nm, photobiomodulation

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.