Evidence map›Paper›PMID 38804637›Full record

ArticleThe Laryngoscope2024

Voice Disorders and Hearing Loss May Be Additive Risk Factors for Depression in a National Cohort.

Anaïs Rameau, Lauren H Tucker, Michael W Denham, Yung Jee Kang, Nayeon Choi, Mark Lachs, Tony Ehren Rosen, Michael Stewart, Sara Czaja, Justin S Golub

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anaïs RameauDepartment of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College/NewYork-Presbyterian, Sean Parker Institute for the Voice, New York, New York, U.S.A.ORCID 0000-0003-1543-2634
Lauren H TuckerDepartment of Otolaryngology-Head and Neck Surgery, Columbia University Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center/NewYork-Presbyterian, New York, New York, U.S.A.ORCID 0009-0006-3247-6515
Michael W DenhamDepartment of Otolaryngology-Head and Neck Surgery, Columbia University Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center/NewYork-Presbyterian, New York, New York, U.S.A.ORCID 0000-0003-0631-5997
Yung Jee KangDepartment of Otolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.ORCID 0000-0003-4062-0717
Nayeon ChoiDepartment of Otolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.ORCID 0000-0002-0962-0594
Mark LachsDivision of Geriatrics and Palliative Medicine, Weill Cornell Medical College/NewYork-Presbyterian, New York, New York, U.S.A.
Tony Ehren RosenDepartment of Emergency Medicine, Weill Cornell Medical College/NewYork-Presbyterian, New York, New York, U.S.A.
Michael StewartDepartment of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College/NewYork-Presbyterian, Sean Parker Institute for the Voice, New York, New York, U.S.A.
Sara CzajaDivision of Geriatrics and Palliative Medicine, Weill Cornell Medical College/NewYork-Presbyterian, New York, New York, U.S.A.
Justin S GolubDepartment of Otolaryngology-Head and Neck Surgery, Columbia University Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center/NewYork-Presbyterian, New York, New York, U.S.A.ORCID 0000-0003-2432-5291

Funding

Bridge2AI: Voice as a Biomarker of Health - Building an ethically sourced, bioaccoustic database to understand disease like never beforeOT2OD032720 · OD · UNIVERSITY OF SOUTH FLORIDA · PI BENSOUSSAN, YAEL EMILIE, BÉLISLE-PIPON, JEAN-CHRISTOPHE · 2022 to 2025
$18.0M
Developing an App-Based Voice Clinical Decision Support Tool to Augment the Sensitivity of the Bedside Swallow Evaluation in Older AdultsK76AG079040 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Anais Rameau · 2022 to 2026
$972k
Mechanisms Linking Hearing Loss and Alzheimer's Disease and Related DementiasK23AG057832 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOLUB, JUSTIN SCOTT · 2018 to 2022
$826k
Common Fund OT2OD032720NIA NIH HHS K23 AG057832NIA NIH HHS K23AG057832NIA NIH HHS K76 AG079040NIA NIH HHS K76AG079040NIH HHS OT2 OD032720
6 · The paper itself

Abstract

objectivesHearing loss (HL) (receptive communication impairment) is a known risk factor for depression. However, dysphonia (expressive communication impairment), has received little study. We study HL, self-reported voice disorder, and combined impairment as risk factors for depression in a large national cohort.

methodsThis was a cross-sectional epidemiologic study. Data were analyzed from the Korean National Health and Nutrition Examination Survey (KNHANES) cycles 2008-2012 and 2019-2020. KNHANES uniquely contains both audiometry and voice disorder data. HL (yes/no) was defined as ≥25 dB pure tone average. Voice disorder (yes/no) was defined by self-report. Depression (yes/no) was defined by physician diagnosis. Odds ratios for depression were calculated using multivariable logistic regressions with HL and voice disorder.

results8,524 individuals aged 19 to 80 years old had complete data. The mean age was 57.3 years (SD = 13.4) and 64% were women. All regressions were controlled for age and sex. Those with HL, versus those without, had 1.27 times the odds (95% CI = 1.07-1.52, p = 0.007) of depression. Those with self-reported voice disorder, versus those without, had 1.48 times the odds (1.22-1.78, p < 0.001) of depression. Those with HL and self-reported voice disorder, versus those with neither, had 1.79 times the odds (1.27-2.48, p < 0.001) of depression.

conclusionsThis study demonstrates independent relationships between HL and depression and self-reported voice disorder and depression. Combined HL and self-reported voice disorder had nearly 1.8 times the odds of depression. This is likely due to the grossly additive effect of difficulty with incoming and outgoing communication streams. LEVEL OF EVIDENCE: II Laryngoscope, 134:4060-4065, 2024.

Indexed as

DepressionHearing LossVoice DisordersAdultAgedAged, 80 and overCohort StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysRepublic of KoreaRisk FactorsSelf Reportdepressiondysphoniahearing loss

Identifiers

PMID38804637
PMCPMC11305957

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.