Evidence map›Paper›PMID 38804388›Full record

ArticleClinics and practice2024

The Contribution of Genetic Testing in Optimizing Therapy for Patients with Recurrent Depressive Disorder.

Rita Ioana Platona, Florica Voiță-Mekeres, Cristina Tudoran, Mariana Tudoran, Virgil Radu Enătescu

Abstract read
In one paragraph

Article in Clinics and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rita Ioana PlatonaDoctoral School, University of Medicine and Pharmacy "Victor Babes" Timisoara, 300041 Timisoara, Romania.
Florica Voiță-MekeresPsychiatry Department, County Clinical Emergency Hospital of Oradea, 410169 Oradea, Romania.ORCID 0000-0002-5960-9043
Cristina TudoranDepartment VII, Internal Medicine II, Discipline of Cardiology, University of Medicine and Pharmacy "Victor Babes" Timisoara, E. Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0000-0002-7351-741X
Mariana TudoranDepartment VII, Internal Medicine II, Discipline of Cardiology, University of Medicine and Pharmacy "Victor Babes" Timisoara, E. Murgu Square, No. 2, 300041 Timisoara, Romania.
Virgil Radu EnătescuCardiology Clinic, County Emergency Hospital "Pius Brinzeu", L. Rebreanu, No. 156, 300723 Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The aim of this study was to analyze the impact of pharmacogenetic-guided antidepressant therapy on the 12-month evolution of the intensity of depressive symptoms in patients with recurrent depressive disorder (RDD) in comparison to a control group of depressive subjects who were treated conventionally. (2) Methods: This prospective longitudinal study was conducted between 2019 and 2022, and the patients were evaluated by employing the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A) and the Clinical Global Impressions Scale: Severity and Improvement. We followed them up at 1, 3, 6, and 12 months. (3) Results: Of the 76 patients with RDD, 37 were tested genetically (Group A) and 39 were not (Group B). Although the patients from Group A had statistically significantly more severe MDD at baseline than those from Group B (

Indexed as

genetic testingmajor depressive disorderpharmacogenetic-guided therapyrecurrent depressive disorderscales for assessing the intensity and evolution of depression

Identifiers

PMID38804388
PMCPMC11130888

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.