Evidence map›Paper›PMID 38804232›Full record

ArticleMolecular and cellular biology2024

Regulation of Betaine Homocysteine Methyltransferase by Liver Receptor Homolog-1 in the Methionine Cycle.

Hee-Kyung Han, Sulagna Mukherjee, Soo-Young Park, Jae-Ho Lee, Eun-Ho Lee, Suji Kim, Yun Han Lee, Dae-Kyu Song, Sooyeun Lee, Jae-Hoon Bae and 1 more

Abstract read
In one paragraph

Article in Molecular and cellular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hee-Kyung HanDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.
Sulagna MukherjeeDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.
Soo-Young ParkDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.
Jae-Ho LeeDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.
Eun-Ho LeeDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.
Suji KimCollege of Pharmacy, Keimyung University, Daegu, Republic of Korea.
Yun Han LeeDepartment of Molecular Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea.
Dae-Kyu SongDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.
Sooyeun LeeCollege of Pharmacy, Keimyung University, Daegu, Republic of Korea.
Jae-Hoon BaeDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.
Seung-Soon ImDepartment of Physiology, Keimyung University School of Medicine, Daegu, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Betaine-homocysteine S-methyltransferase (BHMT) is one of the most abundant proteins in the liver and regulates homocysteine metabolism. However, the molecular mechanisms underlying

Indexed as

Betaine-Homocysteine S-MethyltransferaseHepatocytesLiverMethionineMice, KnockoutReactive Oxygen SpeciesReceptors, Cytoplasmic and NuclearTriglyceridesAnimalsLipid PeroxidationMaleMiceMice, Inbred C57BLMitochondriaPromoter Regions, GeneticBetaine-Homocysteine S-MethyltransferaseBhmt protein, mouseMethionineNr5a2 protein, mouseReactive Oxygen SpeciesReceptors, Cytoplasmic and NuclearTriglyceridesBHMTliverLRH-1methionine cycletriglycerides

Identifiers

PMID38804232
PMCPMC11204035

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.