Evidence map›Paper›PMID 38803946›Full record

ArticleHeliyon2024

Comparison of fidaxomicin, metronidazole and vancomycin for initial episode and recurrence of

Marcos Hernando-Gozalo, Carlos Rescalvo-Casas, Laura Seijas-Pereda, Juan Cuadros-González, Ramón Pérez-Tanoira

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Antimicrobial Susceptibility ofAntibiotics (Basel, Switzerland) · 2026
    Article
  2. Trends and Efficacy in Clostridioides difficile Infection Management at a Polish Clinical Hospital.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  3. Molecular Epidemiology ofAntibiotics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marcos Hernando-GozaloUniversidad de Alcalá, Departamento de Química Orgánica y Química Inorgánica, Instituto de Investigación en Química "Andrés M. del Río" (IQAR), 28805, Madrid, Spain.
Carlos Rescalvo-CasasDepartamento de Microbiología Clínica, Hospital Universitario Príncipe de Asturias, 28805, Madrid, Spain.
Laura Seijas-PeredaDepartamento de Microbiología Clínica, Hospital Universitario Príncipe de Asturias, 28805, Madrid, Spain.
Juan Cuadros-GonzálezDepartamento de Microbiología Clínica, Hospital Universitario Príncipe de Asturias, 28805, Madrid, Spain.
Ramón Pérez-TanoiraDepartamento de Microbiología Clínica, Hospital Universitario Príncipe de Asturias, 28805, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The main aim of this study was to compare the clinical outcomes of patients attended in our area with Methods: A retrospective, cross-sectional and observational study was conducted between June 2022 and June 2023 to compare the clinical cure and/or recurrence of CDI in adult patients treated in a Spanish secondary Hospital depending on the prescribed antibiotic treatment. In addition, we performed an antimicrobial susceptibility study to vancomycin and metronidazole in all Results: Out of 194 selected patients the treatments were as follow: 43.81 % vancomycin, 21.65 % metronidazole, 8.25 % a combination of both, 6.70 % fidaxomicin and 19.59 % were untreated. Vancomycin and fidaxomicin patients had higher odds ratio of prolonged hospitalization ( Conclusion: Fidaxomicin treated patients had statistically increased odds of rCDI. Compared to other treatments, fidaxomicin was inferior to metronidazole for rCDI in our cohort;Hypervirulent

Indexed as

Clostridioides difficileFidaxomicinHypervirulent Clostridioides difficileMetronidazoleRecurrent Clostridioides difficile infectionVancomycin

Identifiers

PMID38803946
PMCPMC11128465

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.