Evidence map›Paper›PMID 38803665›Full record

ArticleFrontiers in cardiovascular medicine2024

Non-linear association and benchmark dose of blood pressure on carotid artery intima-media thickening in a general population of southern China.

Linyuan Qin, Xiaoyan Wu, Chao Tan, Zhengbao Zhang, You Li, Xiaonian Zhu, Shenghua Qin, Shengkui Tan

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Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Linyuan QinDepartment of Epidemiology and Health Statistics, School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
Xiaoyan WuDepartment of Epidemiology and Health Statistics, School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
Chao TanDepartment of Epidemiology and Health Statistics, School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
Zhengbao ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
You LiDepartment of Epidemiology and Health Statistics, School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
Xiaonian ZhuDepartment of Epidemiology and Health Statistics, School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
Shenghua QinPhysical Examination Center, Guilin People's Hospital, Guilin, Guangxi, China.
Shengkui TanDepartment of Epidemiology and Health Statistics, School of Public Health, Guilin Medical University, Guilin, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: This study aimed to evaluate whether there is a J-curve association between blood pressure (BP) and carotid artery intima-media thickening (CAIT) and estimate the effect of the turning point of BP on CAIT. Methods and results: Data from 111,494 regular physical examinations conducted on workers and retirees (aged 18 years or older) between January 2011 and December 2016, exported from the hospital information system, were analyzed. Restricted cubic splines (RCS) logistic regression was employed to access the association of BP with CAIT, and Bayesian benchmark dose methods were used to estimate the benchmark dose as the departure point of BP measurements. All the Conclusion: The J-curve associations between SBP and DBP and the risk of CAIT were observed in the general population in southern China, and the turning point of blood pressure for significantly reducing the risk of CAIT was estimated to be 120.64/72.46 mmHg for SBP/DBP.

Indexed as

benchmark doseblood pressurecarotid artery intima-media thickeningnon-linear associationrestricted cubic splines

Identifiers

PMID38803665
PMCPMC11128656

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