Evidence map›Paper›PMID 38803206›Full record

ArticleActa dermato-venereologica2024

The Burden of Multiple Basal Cell Carcinomas: A Population-wide Study.

Johan Kappelin, Ingela Ahnlide, Åsa Ingvar, Kari Nielsen

Abstract read
In one paragraph

Article in Acta dermato-venereologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Johan KappelinDepartment of Clinical Sciences Lund, Dermatology, Lund University Skin Cancer Research group, Lund University, Lund, Sweden; Dermatology Department, Landskrona Hospital, Landskrona, Sweden. johan.kappelin@med.lu.se.
Ingela AhnlideDepartment of Clinical Sciences Lund, Dermatology, Lund University Skin Cancer Research group, Lund University, Lund, Sweden; Dermatology Department, Landskrona Hospital, Landskrona, Sweden.
Åsa IngvarDepartment of Clinical Sciences Lund, Dermatology, Lund University Skin Cancer Research group, Lund University, Lund, Sweden; Skåne University Hospital, Lund, Sweden.
Kari NielsenDepartment of Clinical Sciences Lund, Dermatology, Lund University Skin Cancer Research group, Lund University, Lund, Sweden; Skåne University Hospital, Lund, Sweden; Department of Clinical Sciences Helsingborg, Dermatology, Lund University, Lund, Sweden; Helsingborg Hospital, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basal cell carcinoma (BCC) is a common skin cancer type and affected individuals are known to be at risk of developing multiple consecutive tumours. Research into BCC multiplicity has, thus far, been challenging, due to a lack of national registration. This registry-based cohort study aimed to analyse the occurrence of multiple BCCs in Sweden, and risk factors for subsequent primary BCCs. Data regarding all histopathologically verified, primary BCC tumours in Sweden from 2004 to 2017 was extracted from the Swedish BCC Registry. Risk of developing a subsequent BCC in relation to person-related factors was estimated with Cox regression analysis. Cumulative risk of BCC development after 1 or 3 earlier BCCs was estimated. In total, 39.9% of individuals with a registered BCC had at least 2 registered tumours. The risk of developing a subsequent BCC increased significantly in males, older age, and with residence in southern Sweden. The cumulative 5-year risk of developing an additional BCC after first diagnosis was approximately 30% in males and 27% in females and increased after multiple previous BCCs. This study showed the cumulative risk of a subsequent BCC to increase with a history of multiple BCCs, indicating the need for clinical surveillance in these individuals.

Indexed as

Basal Cell CarcinomaRegistriesSkin NeoplasmsAdultAgedAged, 80 and overAge FactorsFemaleHamartoma Syndrome, MultipleHumansMaleMiddle AgedNeoplasms, Multiple PrimaryRisk AssessmentRisk FactorsSex Factors

Identifiers

PMID38803206
PMCPMC11151493

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.