ArticleAutism research : official journal of the International Society for Autism Research2024
Profiles of minimally verbal autistic children: Illuminating the neglected end of the spectrum.
Article in Autism research : official journal of the International Society for Autism Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multisite Randomized Control Treatment of Early Intervention for Spoken Communication in Autism
Adaptive Interventions for Minimally Verbal Children With ASD in the Community
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions to Promote Communication in Minimally Verbal Autistic Children: A Systematic Review.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Zebrafish behavioral phenomics reveals functional subtypes of autism risk genes.Molecular psychiatry · 2026Article
- Do Child Communicative Abilities Predict Subjective Wellbeing and Satisfaction With Family Life in Caregivers of Minimally Verbal Children?Journal of autism and developmental disorders · 2026Article
- <p>Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)</p>.International journal of molecular medicine · 2026Review
- Sub-groups of spoken language and broader communication skills in a large heterogenous cohort of minimally verbal school-age children: evidence of discrepant profiles.Molecular autism · 2026Article
- Proportion and Profile of Autistic Children Not Acquiring Spoken Language Despite Receiving Evidence-Based Early Interventions.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2025Article
- Language impairment in autistic adolescents and young adults: Variability by definition.medRxiv : the preprint server for health sciences · 2025Article
- Enhancing Communication in Minimally Verbal Autistic Children: A Study on NAO-Assisted Therapy.Journal of clinical medicine · 2025Article
- Off-Body Sleep Analysis for Predicting Adverse Behavior in Individuals With Autism Spectrum Disorder.IEEE journal of biomedical and health informatics · 2024Article
- Hand Leading in Autism: Associations With Neurocognitive Profiles and Adaptive Abilities.Autism & developmental language impairmentsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Heterogeneity among individuals on the autism spectrum is widely acknowledged as a barrier to develop effective interventions. Overcoming this challenge requires characterization of individual differences, especially for children that are minimally verbal and often excluded from research studies. Most studies that describe autistic subgroups identify a single minimally verbal verbal group based on a single identifying measure (e.g., ADOS module one or single item indicating absence of phrase speech). Determining personalized courses of intervention requires a more detailed understanding since a single intervention will not be effective for all who are minimally verbal. The present study identified comprehensive profiles of cognitive, language, and social communication skills within a large, diverse, group of minimally verbal children with autism. The analysis combined baseline data from two studies to yield a sample of 344 participants, who were 3 to 8 years old at the time of study onset, with 60% who identified as having a race/ethnicity other than White. Via latent profile analysis (LPA), a three-group model was identified as best fit to the data. Profile identification was dependent on a participant's combination of cognitive, expressive, and social communication characteristics, rather than a single domain. One group (n = 206) had global delays, while the other two groups (n = 95 and n = 43) had variable strengths in cognition and communication. Findings suggest that low-frequency/minimally verbal communicators with autism have heterogeneous characteristics that can be systematically organized.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.