Evidence map›Paper›PMID 38802917›Full record

ReviewZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2024

[Advances in Mendelian randomization studies on autism spectrum disorder].

Yun-Yang Hu, Geng-Chang Tian, Meng Liu, Hong Wang

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yun-Yang HuDepartment of Child Health, Maternal and Child Health Hospital of Hubei Province,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China.
Geng-Chang TianDepartment of Child Health, Maternal and Child Health Hospital of Hubei Province,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China.
Meng LiuDepartment of Child Health, Maternal and Child Health Hospital of Hubei Province,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China.
Hong WangDepartment of Child Health, Maternal and Child Health Hospital of Hubei Province,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with onset in infancy or early childhood. Mendelian randomization (MR) is a statistical method used to infer causal relationships between exposures and outcomes. This article summarizes MR studies related to ASD. Existing research supports a causal relationship between maternal inflammatory bowel disease in children with ASD, parental education levels, screen time exposure, obesity, insomnia, serum transferrin, decreased blood selenium, abnormal signals in brain functional MRI, interleukin-6, phosphodiesterase 2A, mitogen-activated protein kinase kinase 3, mitochondrial ribosomal protein L33, serotonin, and ASD. However, it does not support a causal relationship between parental rheumatoid arthritis, systemic lupus erythematosus, neonatal jaundice in children with ASD, cytomegalovirus infection, asthma, oral ulcers, vitamin D levels, and ASD. This article reviews the etiological factors related to ASD and MR studies, aiming to explore and deepen the understanding of the pathophysiology of ASD. It provides strong statistical support for the prevention, diagnosis, and treatment of ASD, and offers new methods and strategies for the etiological analysis of complex traits.

Indexed as

Autism Spectrum DisorderMendelian Randomization AnalysisHumansAutism spectrum disorderChildMendelian randomizationResearch advance

Identifiers

PMID38802917
PMCPMC11135060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.