ArticleBreast cancer research : BCR2024
Breast cancer patients enrolled in the Swiss mammography screening program "donna" demonstrate prolonged survival.
Article in Breast cancer research : BCR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- AI performance varies considerably across mammography devices: a multi-site and multi-vendor retrospective study.Insights into imaging · 2026Article
- Retrospective evaluation of interval breast cancer screening mammograms by radiologists and AI.European radiology · 2026Article
- Socio-Demographic Inequalities in Diagnostic Delays of Breast Cancer: A Multistage Time-to-Diagnosis Analysis.Current oncology (Toronto, Ont.) · 2025Article
- Screen-Detected Breast Cancer Outcomes by Mammography Participation in Immediate Past Screening.JAMA network open · 2025Article
- Risk factors for interval breast cancer: insights from a decade of a mammography screening program.Breast cancer research and treatment · 2025Article
- [The possible benefit of artificial intelligence in an organized population-related screening program : Initial results and perspective].Radiologie (Heidelberg, Germany) · 2024Article
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Abstract
study goalWe compared the survival rates of women with breast cancer (BC) detected within versus outside the mammography screening program (MSP) "donna".
methodsWe merged data from the MSP with the data from corresponding cancer registries to categorize BC cases as within MSP (screen-detected and interval carcinomas) and outside the MSP. We analyzed the tumor stage distribution, tumor characteristics and the survival of the women. We further estimated hazard ratios using Cox-regressions to account for different characteristics between groups and corrected the survival rates for lead-time bias.
resultsWe identified 1057 invasive (ICD-10: C50) and in-situ (D05) BC cases within the MSP and 1501 outside the MSP between 2010 and 2019 in the Swiss cantons of St. Gallen and Grisons. BC within the MSP had a higher share of stage I carcinoma (46.5% vs. 33.0%; p < 0.01), a smaller (mean) tumor size (19.1 mm vs. 24.9 mm, p < 0.01), and fewer recurrences and metastases in the follow-up period (6.7% vs. 15.6%, p < 0.01). The 10-year survival rates were 91.4% for women within and 72.1% for women outside the MSP (p < 0.05). Survival difference persisted but decreased when women within the same tumor stage were compared. Lead-time corrected hazard ratios for the MSP accounted for age, tumor size and Ki-67 proliferation index were 0.550 (95% CI 0.389, 0.778; p < 0.01) for overall survival and 0.469 (95% CI 0.294, 0.749; p < 0.01) for BC related survival.
conclusionWomen participating in the "donna" MSP had a significantly higher overall and BC related survival rate than women outside the program. Detection of BC at an earlier tumor stage only partially explains the observed differences.
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