Evidence map›Paper›PMID 38802680›Full record

ArticleAnalytical and bioanalytical chemistry2024

Real-time monitoring of intracellular biochemical response in locally stretched single cell by a nanosensor.

Xue-Ke Jin, Kai-Qi Jin, Xiao-Ke Yang, Ming-Yong Wen, Yan-Ling Liu, Wei-Hua Huang

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xue-Ke Jin *College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Kai-Qi Jin *College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Xiao-Ke YangCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Ming-Yong WenCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Yan-Ling LiuCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Wei-Hua HuangCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China. whhuang@whu.edu.cn.

Funding

National Natural Science Foundation of China 22090050；22090051
6 · The paper itself

Abstract

Mechanotransduction is the essential process that cells convert mechanical force into biochemical responses, and electrochemical sensor stands out from existing techniques by providing quantitative and real-time information about the biochemical signals during cellular mechanotransduction. However, the intracellular biochemical response evoked by mechanical force has been poorly monitored. In this paper, we report a method to apply local stretch on single cell and simultaneously monitor the ensuing intracellular biochemical signals. Specifically, a ferromagnetic micropipette was fabricated to locally stretch a single cell labeled with Fe

Indexed as

Hydrogen PeroxideMechanotransduction, CellularNanowiresSingle-Cell AnalysisBiosensing TechniquesElectrochemical TechniquesElectrodesHumansPlatinumHydrogen PeroxidePlatinumBiochemical responseElectrochemical sensorMagnetic manipulationNanoelectrodeSingle cell

Identifiers

PMID38802680

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.