Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Anthony L HesselInstitute of Physiology II, University of Muenster, Muenster, Germany. anthony.hessel@uni-muenster.de.ORCID 0000-0003-4278-4221
Michel N KuehnInstitute of Physiology II, University of Muenster, Muenster, Germany.
Seong-Won HanInstitute of Physiology II, University of Muenster, Muenster, Germany.
Weikang MaBioCAT, Department of Biology, Illinois Institute of Technology, Chicago, USA.ORCID 0000-0001-9535-7114
Thomas C IrvingBioCAT, Department of Biology, Illinois Institute of Technology, Chicago, USA.
Brent A MombDepartment of Kinesiology, University of Massachusetts-Amherst, Amherst, MA, USA.
Taejeong SongCenter for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.ORCID 0000-0001-6648-1263
Sakthivel SadayappanCenter for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.ORCID 0000-0003-2006-7678
Wolfgang A LinkeInstitute of Physiology II, University of Muenster, Muenster, Germany.ORCID 0000-0003-0801-3773
Bradley M PalmerDepartment of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, USA. Bradley.palmer@uvm.edu.ORCID 0000-0002-4388-3160
Funding
Ventricular and Cardiac Fiber Characterization and Integration CoreP01HL059408 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI ROBBINS, JEFFREY · 1999 to 2014
$26.4M
The Biophysics Collaborative Access Team (User Training and Outreach)P30GM138395 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI THOMAS C IRVING · 2021 to 2026
$16.5M
Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
Fast myosin binding protein-C and cardiac contractility in heart failureR01HL105826 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2011 to 2025
$4.5M
Skeletal muscle sarcomere function in health and diseaseR01AR079477 · NIAMS · UNIVERSITY OF MINNESOTA · PI JOSEPH Mark METZGER · 2022 to 2026
$2.6M
Skeletal Myosin-Binding Protein C Regulation and Structural DynamicsR01AR079435 · NIAMS · UNIVERSITY OF ARIZONA · PI Brett A Colson · 2022 to 2026
$2.4M
Research supplement to promote diversity in Heath-related researchR01HL150953 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SIVARAMAKRISHNAN, SIVARAJ, WARSHAW, DAVID M · 2020 to 2023
$2.4M
Slow myosin binding protein-C in skeletal muscle physiologyR01AR078001 · NIAMS · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2020 to 2023
$1.8M
IGF-2R is a new therapeutic target for cardiac ischemia-reperfusion injuryR01HL143490 · NHLBI · UNIVERSITY OF CINCINNATI · PI WANG, YIGANG · 2019 to 2022
$1.6M
Molecular mechanism of hypertrophic cardiomyopathy in populations of South Asian descendantsR01HL130356 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2016 to 2019
$1.6M
Thick filament regulation mechanisms in healthy and diseased myocardiumR01HL171657 · NHLBI · ILLINOIS INSTITUTE OF TECHNOLOGY · PI Weikang Ma · 2024 to 2026
In striated muscle, the sarcomeric protein myosin-binding protein-C (MyBP-C) is bound to the myosin thick filament and is predicted to stabilize myosin heads in a docked position against the thick filament, which limits crossbridge formation. Here, we use the homozygous Mybpc2 knockout (C2
Indexed as
Carrier ProteinsMice, KnockoutActin CytoskeletonAnimalsMaleMiceMuscle, SkeletalMyofibrilsMyosin Binding Protein CMyosinsSarcomeresCarrier ProteinsMyosin Binding Protein CMyosins
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure. · full record | OpenQuestion