ArticleNature communications2024
Enhanced surface colonisation and competition during bacterial adaptation to a fungus.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Harnessing plant-microbe interactions: strategies for enhancing resilience and nutrient acquisition for sustainable agriculture.Frontiers in plant science · 2025Pooled it
- Phage-ICE tandems facilitate bacterial adaptation and antimicrobial resistance spread.Science advances · 2026Article
- Review
- Synthetic microbial communities for studying the fate and ecological role of specialized metabolites.Essays in biochemistry · 2026Review
- The aquatic plastisphere: ecology, pathogen dissemination and antimicrobial resistance.Nature reviews. Microbiology · 2026Review
- Article
- Mechanisms ofAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Metabolite interactions mediate beneficial alliances between Bacillus and Trichoderma for effective Fusarium wilt control.The ISME journal · 2026Article
- EngineeredBioactive materials · 2025Article
- Soft X-ray tomography reveals variations in B. subtilis biofilm structure upon tasA deletion.NPJ biofilms and microbiomes · 2025Article
- Diversification of Lipopeptide Analogues Drives Versatility in Biological Activities.Journal of agricultural and food chemistry · 2025Article
- In vitro and In silico investigation deciphering novel antifungal activity of endophyte Bacillus velezensis CBMB205 against Fusarium oxysporum.Scientific reports · 2025Article
- Fungi shape genome evolution of bacteria even in the absence of major growth phenotypes.The ISME journal · 2025Article
- Fungal hyphae promote bacterial contact-dependent killing during surface-associated growth.The ISME journal · 2025Article
- Presence of a biofilm beneficiary alters the evolutionary trajectory of a biofilm former.The ISME journal · 2025Article
- Ecological dynamics and microbial community composition ofFrontiers in microbiology · 2025Article
- Article
- Subtilosin A production is influenced by surfactin levels inmicroLife · 2025Article
- Unlocking the potential of experimental evolution to study drug resistance in pathogenic fungi.npj antimicrobials and resistance · 2024Review
- Taxonomy ofmSystems · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Funding
Abstract
Bacterial-fungal interactions influence microbial community performance of most ecosystems and elicit specific microbial behaviours, including stimulating specialised metabolite production. Here, we use a co-culture experimental evolution approach to investigate bacterial adaptation to the presence of a fungus, using a simple model of bacterial-fungal interactions encompassing the bacterium Bacillus subtilis and the fungus Aspergillus niger. We find in one evolving population that B. subtilis was selected for enhanced production of the lipopeptide surfactin and accelerated surface spreading ability, leading to inhibition of fungal expansion and acidification of the environment. These phenotypes were explained by specific mutations in the DegS-DegU two-component system. In the presence of surfactin, fungal hyphae exhibited bulging cells with delocalised secretory vesicles possibly provoking an RlmA-dependent cell wall stress. Thus, our results indicate that the presence of the fungus selects for increased surfactin production, which inhibits fungal growth and facilitates the competitive success of the bacterium.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.