Evidence map›Paper›PMID 38802280›Full record

ArticleOpen heart2024

Long COVID and cardiovascular disease: a prospective cohort study.

Claire Alexandra Lawson, Alastair James Moss, Jayanth Ranjit Arnold, Catherine Bagot, Amitava Banerjee, Colin Berry, John Greenwood, Alun D Hughes, Kamlesh Khunti, Nicholas L Mills and 28 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Open heart, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Claire Alexandra LawsonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.ORCID 0000-0003-0127-5236
Alastair James MossDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.ORCID 0000-0003-4123-2070
Jayanth Ranjit ArnoldDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Catherine BagotDepartment of Haemostasis and Thrombosis, Glasgow Royal Infirmary, Glasgow, Glasgow, UK.ORCID 0000-0002-6439-9706
Amitava BanerjeeFarr Institute of Health Informatics Research, University College London, London, UK.ORCID 0000-0001-8741-3411
Colin BerryBHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
John GreenwoodCardiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.ORCID 0000-0002-2861-0914
Alun D HughesMRC Unit for Lifelong Health and Ageing, University College London, London, UK.
Kamlesh KhuntiLeicester Real World Evidence Unit, Leicester Diabetes Centre, University of Leicester, Leicester, UK.
Nicholas L MillsBHF Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, Edinburgh, UK.
Stefan NeubauerRadcliffe Department of Medicine, University of Oxford, Oxford, UK.
Betty RamanRadcliffe Department of Medicine, University of Oxford, Oxford, UK.
Naveed SattarInstitute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
Olivia C LeavyDepartment of Population Health Sciences, University of Leicester, Leicester, UK.
Matthew RichardsonUniversity of Leicester, Leicester, UK.
Omer ElneimaUniversity of Leicester, Leicester, UK.
Hamish Jc McAuleyUniversity of Leicester, Leicester, UK.
Aarti ShikotraUniversity of Leicester, Leicester, UK.
Amisha SingapuriUniversity of Leicester, Leicester, UK.
Marco SerenoUniversity of Leicester, Leicester, UK.
Ruth SaundersUniversity of Leicester, Leicester, UK.
Victoria HarrisUniversity of Leicester, Leicester, UK.
Linzy Houchen-WolloffUniversity of Leicester, Leicester, UK.ORCID 0000-0003-4940-8835
Neil J GreeningUniversity of Leicester, Leicester, UK.
Ewen HarrisonUniversity of Edinburgh, Edinburgh, UK.
Annemarie B DochertyUniversity of Edinburgh, Edinburgh, UK.
Nazir I LoneUniversity of Edinburgh, Edinburgh, UK.
Jennifer Kathleen QuintNHLI, Imperial College London, London, UK.ORCID 0000-0003-0149-4869
James ChalmersUniversity of Dundee, Dundee, Dundee, UK.
Ling-Pei HoUniversity of Oxford, Oxford, UK.
Alex HorsleyUniversity of Manchester, Manchester, UK.
Michael MarksDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.
Krisnah PoinasamyAsthma and Lung UK, London, UK.
Rachael EvansThe Institute for Lung Health, University of Leicester, Leicester, UK.
Louise V WainDepartment of Population Health Sciences, University of Leicester, Leicester, UK.
Chris BrightlingThe Institute for Lung Health, University of Leicester, Leicester, UK.
Gerry P McCannDepartment of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK gpm12@leicester.ac.uk.ORCID 0000-0002-5542-8448
PHOSP-COVID Study Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPre-existing cardiovascular disease (CVD) or cardiovascular risk factors have been associated with an increased risk of complications following hospitalisation with COVID-19, but their impact on the rate of recovery following discharge is not known.

objectivesTo determine whether the rate of patient-perceived recovery following hospitalisation with COVID-19 was affected by the presence of CVD or cardiovascular risk factors.

methodsIn a multicentre prospective cohort study, patients were recruited following discharge from the hospital with COVID-19 undertaking two comprehensive assessments at 5 months and 12 months. Patients were stratified by the presence of either CVD or cardiovascular risk factors prior to hospitalisation with COVID-19 and compared with controls with neither. Full recovery was determined by the response to a patient-perceived evaluation of full recovery from COVID-19 in the context of physical, physiological and cognitive determinants of health.

resultsFrom a total population of 2545 patients (38.8% women), 472 (18.5%) and 1355 (53.2%) had CVD or cardiovascular risk factors, respectively. Compared with controls (n=718), patients with CVD and cardiovascular risk factors were older and more likely to have had severe COVID-19. Full recovery was significantly lower at 12 months in patients with CVD (adjusted OR (aOR) 0.62, 95% CI 0.43 to 0.89) and cardiovascular risk factors (aOR 0.66, 95% CI 0.50 to 0.86).

conclusionPatients with CVD or cardiovascular risk factors had a delayed recovery at 12 months following hospitalisation with COVID-19. Targeted interventions to reduce the impact of COVID-19 in patients with cardiovascular disease remain an unmet need. TRAIL REGISTRATION NUMBER: ISRCTN10980107.

Indexed as

Cardiovascular DiseasesCOVID-19AgedFemaleHospitalizationHumansMaleMiddle AgedProspective StudiesRecovery of FunctionRisk FactorsSARS-CoV-2Time FactorsCARDIAC REHABILITATIONCOVID-19RISK FACTORS

Identifiers

PMID38802280
PMCPMC11131117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.