Evidence map›Paper›PMID 38802079›Full record

ArticleAmerican journal of perinatology2024

Association between Neonatal Outcomes and Admission Hypothermia among Very Preterm Infants in Chinese Neonatal Intensive Care Units: A Multicenter Cohort Study.

Wenchao Hong, Yanping Zhu, Yanchen Wang, Siyuan Jiang, Yun Cao, Xinyue Gu, Shoo K Lee, Sheree Kuo, Jianhua Sun, Yuan Shi and 3 more

Abstract readMulticenter Study
In one paragraph

Article in American journal of perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wenchao HongDepartment of Neonatology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yanping ZhuDepartment of Neonatology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Yanchen WangDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Siyuan JiangDepartment of Neonatology, Children's Hospital of Fudan University, Minhang District, Shanghai, China.
Yun CaoDepartment of Neonatology, Children's Hospital of Fudan University, Minhang District, Shanghai, China.
Xinyue GuDepartment of Neonatology, Children's Hospital of Fudan University, Minhang District, Shanghai, China.
Shoo K LeeMaternal Infant Care Research Center, Mount Sinai Hospital, Toronto, Ontario, Canada.
Sheree KuoDepartment of Pediatrics, John A. Burns School of Medicine and Kapiolani Medical Center for Women and Children, University of Hawaii, Honolulu, Hawaii.
Jianhua SunDepartment of Neonatology, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yuan ShiDepartment of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Chongbing YanDepartment of Neonatology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Mingxia LiDepartment of Neonatology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Xiaohui GongDepartment of Neonatology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to investigate the relationship between admission hypothermia and outcomes among very preterm infants (VPIs) in neonatal intensive care units (NICUs) in China. We also investigated the frequency of hypothermia in VPIs in China and the variation in hypothermia across Chinese Neonatal Network (CHNN) sites. STUDY

designThis retrospective cohort study enrolled infants with 24

resultsA total of 5,913 VPIs were included in this study, of which 4,075 (68.9%) had hypothermia (<36.5 °C) at admission. The incidence of admission hypothermia varied widely across CHNN sites (9-100%). Lower gestational age (GA), lower birth weight, antenatal steroid administration, multiple births, small for GA, Apgar scores <7 at the 5th minute, and intensive resuscitation were significantly associated with admission hypothermia. Compared with infants with normothermia (36.5-37.5 °C), the adjusted odds ratios (ORs) for composite outcome among infants with admission hypothermia <35.5 °C increased to 1.47 (95% confidence interval [CI], 1.15-1.88). The adjusted ORs for mortality among infants with admission hypothermia (36.0-36.4 and <35.5 °C) increased to 1.41 (95% CI, 1.09-1.83) and 1.93 (95% CI, 1.31-2.85), respectively. Admission hypothermia was associated with a higher likelihood of bronchopulmonary dysplasia, but was not associated with necrotizing enterocolitis ≥stage II, severe intraventricular hemorrhage, cystic periventricular leukomalacia, severe retinopathy of prematurity, or sepsis.

conclusionAdmission hypothermia remains a common problem for VPIs in a large cohort in China and is associated with adverse outcomes. Continuous quality improvement of admission hypothermia in the future may result in a substantial improvement in the outcomes of VPIs in China. KEY POINTS: · Admission hypothermia is common in VPIs.. · The incidence of admission hypothermia in VPIs remains high in China.. · Admission hypothermia is associated with adverse outcomes in VPIs..

Indexed as

HypothermiaIntensive Care Units, NeonatalChinaEast Asian PeopleFemaleGestational AgeHumansIncidenceInfant, Extremely PrematureInfant, NewbornInfant, Premature, DiseasesMaleRetrospective StudiesRisk Factors

Identifiers

PMID38802079
PMCPMC11534463

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.