Evidence map›Paper›PMID 38801653›Full record

ArticleACS nano2024

Multimodal Imaging-Guided Stem Cell Ocular Treatment.

Van Phuc Nguyen, Athanasios J Karoukis, Wei Qian, Lisheng Chen, Nirosha D Perera, Dongshan Yang, Qitao Zhang, Josh Zhe, Jessica Henry, Bing Liu and 4 more

Abstract read
In one paragraph

Article in ACS nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Long-Term Diabetic Retinopathy Treatment Using Silicon Nanoneedles.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Van Phuc NguyenDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.ORCID 0000-0001-7466-1483
Athanasios J KaroukisDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.
Wei QianIMRA America Inc., Ann Arbor, Michigan 48105, United States.
Lisheng ChenDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.
Nirosha D PereraDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.
Dongshan YangCenter for Advanced Models for Translational Sciences and Therapeutics, University of Michigan, Ann Arbor, Michigan 48109, United States.
Qitao ZhangDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.
Josh ZheDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.
Jessica HenryDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.
Bing LiuIMRA America Inc., Ann Arbor, Michigan 48105, United States.
Wei ZhangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, United States.
Abigail T FahimDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.
Xueding WangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48105, United States.ORCID 0000-0002-2974-6258
Yannis M PaulusDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, United States.ORCID 0000-0002-0615-628X

Funding

VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Peter F Hitchcock · 1987 to 2026
$17.6M
Multimodal Molecular Imaging of Choroidal NeovascularizationR01EY034325 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Yannis Mantas Paulus, XUEDING WANG · 2023 to 2026
$2.5M
Development of Nanoneedle Array for Painless and Long-Term Sustained Intraocular Drug DeliveryR01EY033000 · NEI · PURDUE UNIVERSITY · PI LEE, CHI HWAN, PAULUS, YANNIS MANTAS · 2021 to 2025
$1.9M
Real-time In Vivo Visualization of the Molecular Processes in Choroidal NeovascularizationK08EY027458 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PAULUS, YANNIS MANTAS · 2018 to 2021
$898k
Investigating Membrane Trafficking Deficits in ChoroideremiaK08EY032991 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FAHIM, ABIGAIL · 2021 to 2023
$713k
NEI NIH HHS K08 EY027458NEI NIH HHS K08 EY032991NEI NIH HHS P30 EY007003NEI NIH HHS R01 EY033000NEI NIH HHS R01 EY034325
6 · The paper itself

Abstract

Stem cell therapies are gaining traction as promising treatments for a variety of degenerative conditions. Both clinical and preclinical studies of regenerative medicine are hampered by the lack of technologies that can evaluate the migration and behavior of stem cells post-transplantation. This study proposes an innovative method to longitudinally image

Indexed as

GoldMultimodal ImagingRetinal Pigment EpitheliumAnimalsCell DifferentiationCell MovementHumansInduced Pluripotent Stem CellsMetal NanoparticlesOptical ImagingPhotoacoustic TechniquesRabbitsStem Cell TransplantationTomography, Optical CoherenceGoldcontrast agentsgold nanochainshuman-induced pluripotent stem cells differentiated to retinal pigment epitheliumoptical coherence tomographyphotoacoustic microscopyregenerative medicinestem cell therapy

Identifiers

PMID38801653
PMCPMC11804834

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.