Evidence map›Paper›PMID 38801444›Full record

SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Experience in endoscope choice for neuroendoscopic lavage for intraventricular hemorrhage of prematurity: a systematic review.

Catherine E Wassef, Ulrich W Thomale, Melissa A LoPresti, Michael G DeCuypere, Jeffrey S Raskin, Shreya Mukherjee, Kristian Aquilina, Sandi K Lam

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Neuroendoscopic lavage: a single-center retrospective cohort in the USA.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Catherine E WassefDepartment of Neurosurgery, University of Rochester Medical Center, Rochester, NY, USA.
Ulrich W ThomalePediatric Neurosurgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Melissa A LoPrestiDepartment of Neurosurgery, University of Rochester Medical Center, Rochester, NY, USA.
Michael G DeCuypereDivision of Pediatric Neurosurgery, Lurie Children's Hospital, 225 E Chicago Ave, Box 28, Chicago, IL, 60611, USA.
Jeffrey S RaskinDivision of Pediatric Neurosurgery, Lurie Children's Hospital, 225 E Chicago Ave, Box 28, Chicago, IL, 60611, USA.
Shreya MukherjeeDivision of Pediatric Neurosurgery, Lurie Children's Hospital, 225 E Chicago Ave, Box 28, Chicago, IL, 60611, USA.
Kristian AquilinaDepartment of Pediatric Neurosurgery, Great Ormond Street Hospital, London, UK.
Sandi K LamDivision of Pediatric Neurosurgery, Lurie Children's Hospital, 225 E Chicago Ave, Box 28, Chicago, IL, 60611, USA. slam@luriechildrens.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIntraventricular hemorrhage (IVH) of prematurity occurs in 20-38% of infants born < 28 weeks gestational age and 15% of infants born in 28-32 weeks gestational age. Treatment has evolved from conservative management and CSF diversion of temporizing and shunting procedures to include strategies aimed at primarily clearing intraventricular blood products. Neuroendoscopic lavage (NEL) aims to decrease the intraventricular blood burden under the same anesthetic as temporizing CSF diversion measures in cases of hydrocephalus from IVH of prematurity. Given the variety of neuroendoscopes, we sought to review the literature and practical considerations to help guide neuroendoscope selection when planning NEL.

methodsWe conducted a systematic review of the literature on neuroendoscopic lavage in IVH of prematurity to examine data on the choice of neuroendoscope and outcomes regarding shunt rate. We then collected manufacturer data on neuroendoscopic devices, including inflow and outflow mechanisms, working channel specifications, and tools compatible with the working channel. We paired this information with the advantages and disadvantages reported in the literature and observations from the experiences of pediatric neurosurgeons from several institutions to provide a pragmatic evaluation of international clinical experience with each neuroendoscope in NEL.

resultsEight studies were identified; four neuroendoscopes have been used for NEL as reported in the literature. These include the Karl Storz Flexible Neuroendoscope, LOTTA

conclusionsA neuroendoscope integrating continuous irrigation, characterized by measured inflow and outflow via separate channels and multiple associated instruments, appears to be the most commonly used technology in the literature. As neuroendoscopes evolve, maximizing clear visualization, adequate inflow, measured outflow, and large enough working channels for paired instrumentation while minimizing the footprint of the outer diameter will be most advantageous when applied for NEL in premature infants.

Indexed as

Infant, PrematureNeuroendoscopyTherapeutic IrrigationCerebral HemorrhageCerebral Intraventricular HemorrhageHumansInfant, NewbornInfant, Premature, DiseasesNeuroendoscopesHydrocephalusIntraventricular hemorrhageNeuroendoscopeNeuroendoscopic lavagePreemie IVHPrematurity

Identifiers

PMID38801444
PMCPMC11269422

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.