Evidence map›Paper›PMID 38801316›Full record

Observational studyJBRA assisted reproduction2024

Low ovarian responders produce more progesterone per follicle than normal and high responders.

Alfredo Cortés-Vazquez, Alfredo Leonardo Cortés-Algara, Daniel Moreno-García, Johnny S Younis

Abstract readObservational Study
In one paragraph

Observational study in JBRA assisted reproduction, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alfredo Cortés-VazquezReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Alfredo Leonardo Cortés-AlgaraMinimally Invasive Gynecology and Robotic Surgery Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Daniel Moreno-GarcíaReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Johnny S YounisAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLate follicular premature progesterone rise is a complex phenomenon encountered during assisted reproductive technology (ART) treatments; different etiologies can occur in the same patient. Low ovarian responders may be the best example, since higher FSH doses and ovarian aging-related changes may interact and generate a premature progesterone rise. This study aims to explore the correlation between progesterone levels on hCG day and the progesterone-to-follicle index and compare the progesterone-to-follicle index according to ovarian response.

methodsWe performed a retrospective, observational, analytic, cross-sectional, and cohort study at the Reproductive Endocrinology Department at Centro Médico Nacional 20 de November between January 2015 to January 2020. After verifying for normalcy, a Spearman Rho, Principal Component Analysis, and a simple linear regression model were performed. Treatment cycles were classified according to their ovarian response. Low-ovarian responders were classified according to the Bologna Criteria. Then an ANOVA test was performed to compare each group.

resultsOur results show that the progesterone-to-follicle index correlates best with progesterone levels on hCG day. Comparing all the ovarian responses, low ovarian responders have the highest progesterone-to-follicle index of the four groups.

conclusionsLow ovarian responders produce more progesterone per follicle than regular and high responders.

Indexed as

Ovarian FollicleOvulation InductionProgesteroneAdultCohort StudiesCross-Sectional StudiesFemaleHumansRetrospective StudiesProgesteronefollicleindexlow respondersprogesterone

Identifiers

PMID38801316
PMCPMC11622415

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.