ArticleJournal of applied clinical medical physics2024
Impact of scatter radiation on spectral quantification performance of first- and second-generation dual-layer spectral computed tomography.
Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Characteristics of liver virtual non-contrast images from three-phase dynamic CT obtained with second-generation dual-layer spectral CT.European journal of radiology open · 2026Article
- Phantom-based quantification of the spectral accuracy of lower extremity vascular imaging using a second-generation dual-layer spectral CT at 100 kVp and 120kVp.BMC medical imaging · 2025Article
- Experimental feasibility of dual-energy X-ray tomography for two-phase density analysis in bentonite during water infiltration.Scientific reports · 2025Article
- Impact of scatter radiation on spectral quantification performance of first- and second-generation dual-layer spectral computed tomography.Journal of applied clinical medical physics · 2024Article
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7 authors.
Funding
Abstract
objectiveTo assess the impact of scatter radiation on quantitative performance of first and second-generation dual-layer spectral computed tomography (DLCT) systems.
methodA phantom with two iodine inserts (1 and 2 mg/mL) configured to intentionally introduce high scattering conditions was scanned with a first- and second-generation DLCT. Collimation widths (maximum of 4 cm for first generation and 8 cm for second generation) and radiation dose levels were varied. To evaluate the performance of both systems, the mean CT numbers of virtual monoenergetic images (MonoEs) at different energies were calculated and compared to expected values. MonoEs at 50 versus 150 keV were plotted to assess material characterization of both DLCTs. Additionally, iodine concentrations were determined, plotted, and compared against expected values. For each experimental scenario, absolute errors were reported.
resultsAn experimental setup, including a phantom design, was successfully implemented to simulate high scatter radiation imaging conditions. Both CT scanners illustrated high spectral accuracy for small collimation widths (1 and 2 cm). With increased collimation (4 cm), the second-generation DLCT outperformed the earlier DLCT system. Further, the spectral performance of the second-generation DLCT at an 8 cm collimation width was comparable to a 4 cm collimation on the first-generation DLCT. A comparison of the absolute errors between both systems at lower energy MonoEs illustrates that, for the same acquisition parameters, the second-generation DLCT generated results with decreased errors. Similarly, the maximum error in iodine quantification was less with second-generation DLCT (0.45 and 0.33 mg/mL for the first and second-generation DLCT, respectively).
conclusionThe implementation of a two-dimensional anti-scatter grid in the second-generation DLCT improves the spectral quantification performance. In the clinical routine, this improvement may enable additional clinical benefits, for example, in lung imaging.
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